Protein Alignment GTF2F2 and TfIIFbeta

DIOPT Version :10

• Sequence 1: XP_011533354.1
• Gene: GTF2F2 / 2963
• HGNCID: 4653
• Length: 275
• Species: Homo sapiens
• Sequence 2: NP_524305.2
• Gene: TfIIFbeta / 41290
• FlyBaseID: FBgn0010421
• Length: 277
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 131/277 - (47%)
• Similarity: 172/277 - (62%)
• Gaps: 32/277 - (11%)

Human     6 ELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQG-RTEVSFTLNEDLANIHDIG 69
            :|||:.|  ..||||||||||::|:|.||....:||||||.||.| :.:||.:|.
  Fly    15 DLDLSNA--GRGVWLVKVPKYIAQKWEKAPTNMDVGKLRINKTPGQKAQVSLSLT---------- 67

Human    70 GKPASVS------APREHPFVLQSVGGQTLTVFTESSSGGSRMTAGVTTVISTSQASKGKQDGED 128
              ||.::      .|.||...:..|..|||.||:..:....:..       ||:.|:   |...:
  Fly    68 --PAVLALDPEEKIPTEHILDVSQVTKQTLGVFSHMAPSDGKEN-------STTSAA---QPDNE 120

Human   129 KLSLEGIVVQRAECRPAASENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYER 193
            ||.:||.:||:.||||.|...||:||...|.::|:|.|..|.:||:| .|:|||.:|.:||||..
  Fly   121 KLYMEGRIVQKLECRPIADNCYMKLKLESIRKASEPQRRVQPIDKIV-QNFKPVKDHAHNIEYRE 184

Human   194 KKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNT 258
            :||.:||:||.||..|:||||.|||||||||:||||.||.||:.|||||||::...|:|..|||.
  Fly   185 RKKAEGKKARDDKNAVMDMLFHAFEKHQYYNIKDLVKITNQPISYLKEILKDVCDYNMKNPHKNM 249

Human   259 WELKPEYRHYQGEEKSD 275
            ||||.|||||:.|||.:
  Fly   250 WELKKEYRHYKTEEKKE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GTF2F2	XP_011533354.1	TFIIF_beta	5..144	CDD:259828	53/144 (37%)
		TFIIF_beta	202..266	CDD:426691	43/63 (68%)
TfIIFbeta	NP_524305.2	TFIIF_beta	13..136	CDD:259828	53/144 (37%)
		TFIIF_beta	193..257	CDD:426691	43/63 (68%)