Protein Alignment Pitx3 and otp

DIOPT Version :9

• Sequence 1: NP_062120.1
• Gene: Pitx3 / 29609
• RGDID: 3332
• Length: 302
• Species: Rattus norvegicus
• Sequence 2: NP_001286654.1
• Gene: otp / 37364
• FlyBaseID: FBgn0015524
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 84/291 - (28%)
• Similarity: 120/291 - (41%)
• Gaps: 81/291 - (27%)

  Rat    59 KKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERS 123
            |.||:|.||.||..||.|||..|.:..|||:..|||||:...|||:||:|||:||||||:||:::
  Fly   113 KNKQKRHRTRFTPAQLNELERCFSKTHYPDIFMREEIAMRIGLTESRVQVWFQNRRAKWKKRKKT 177

  Rat   124 QQAELCKGGFAAPLGGLVPPYEEVYPGYTYGNWPPKALAPPLAAKTFPFAFN------------- 175
            ...      |..| |.|:|         ::|       .||..|.....|..
  Fly   178 TNV------FRTP-GALLP---------SHG-------LPPFGANITNIAMGDGLCGTGMFGGDR 219

  Rat   176 -SVNVGPLAS---QPVFSPPSSIAASMVPSAAAAPGTVPGPGALQ--GLGGAPPGLAPAAV---S 231
             ||.|.|:.:   |...|.|.|.:.:...::....|:..|.|:.|  ||.    .|..:.:   |
  Fly   220 WSVGVNPMTAGFGQLNQSSPLSSSLNSGLNSGINMGSALGAGSYQHYGLN----ALGDSMMYQHS 280

  Rat   232 SGAVSC-PYASAAAA------AAAAASSPYVYRDPCNSSLASL-------------------RLK 270
            .|.||| |..|.:|.      :.::.:.|.:...| |||...|                   :.:
  Fly   281 VGGVSCGPSGSPSATTPPNMNSCSSVTPPPLSAQP-NSSQNELNGEPMPLHQQQQQQTHQHQQQQ 344

  Rat   271 AKQHASFSYPAVPGPPPAANLSPCQYAVERP 301
            ..||    :|..| |.|.........:::.|
  Fly   345 THQH----HPMAP-PTPTQQQQQLPQSMQSP 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitx3	NP_062120.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		7/11 (64%)
		Homeobox	66..119	CDD:395001	32/52 (62%)
		PTZ00395	<142..>236	CDD:185594	23/115 (20%)
		OAR	258..275	CDD:397759	6/35 (17%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	262..275		4/31 (13%)
		Nuclear localization signal. /evidence=ECO:0000255	268..272		0/3 (0%)
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	26/47 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I4895
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960