DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ndufs3 and ND-30

DIOPT Version :9

Sequence 1:	NP_001099959.1	Gene:	Ndufs3 / 295923	RGDID:	1309406	Length:	264	Species:	Rattus norvegicus
Sequence 2:	NP_647775.1	Gene:	ND-30 / 38378	FlyBaseID:	FBgn0266582	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	163/266 - (61%)
Similarity:	191/266 - (71%)	Gaps:	7/266 - (2%)

- Green bases have known domain annotations that are detailed below.

  Rat     1 MASAAARVWCRGLLGAAS---VARGAGRPSVLLQQRVRRESAAADKRPTVRPSSDVTHKRLSAFG 62
            ||:....:..|..:.|.|   |...||..::.:......|...||| ||||....|....||.||
  Fly     1 MAALIRNLGARAAVAALSAKHVVPAAGSTALRMASTTPVEPKKADK-PTVRQPDAVARSHLSDFG 64

  Rat    63 EYVAEILPKYVQQVQVTCFDELEICIHPDGVIPTITFLKDHTNAQFKSLADLTAVDVPTRQNRFE 127
            .||||.||||||:||:|..||||:.|.|:||:|.:.|||||..|||.:|.|:..||||.|:||||
  Fly    65 RYVAECLPKYVQKVQLTAGDELEVLIAPEGVVPVLQFLKDHHQAQFTNLVDIAGVDVPCRKNRFE 129

  Rat   128 IVYNLLSLRFNSRIRVKTYADELTAIDSIVSVHIAANWYEREVWDMFGVFFFNHPDLRRILTDYG 192
            :||||||||:|||||||||.||||.:||...||.||||||||:|||:||||.|||||||||||||
  Fly   130 VVYNLLSLRYNSRIRVKTYTDELTPLDSACEVHKAANWYEREIWDMYGVFFANHPDLRRILTDYG 194

  Rat   193 FEGHPFRKDFPLTGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPAYRQ---PPEHLKL 254
            |||||.|:||||:||||||||||.||||.||:|||||||||||::|||.||.:|.   |.|.:..
  Fly   195 FEGHPQRRDFPLSGYVELRYDDEKKRVVCEPLELAQEFRKFDLSAPWEQFPNFRNANPPAEVVPP 259

  Rat   255 EAGDKK 260
            :|..||
  Fly   260 QAPAKK 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndufs3	NP_001099959.1	PRK06074	57..240	CDD:235691	136/182 (75%)
ND-30	NP_647775.1	PRK06074	60..242	CDD:235691	136/181 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354202
Domainoid	1	1.000	198	1.000	Domainoid score	I3001
eggNOG	1	0.900	-	-		E1_COG0852
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3346
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2455
OMA	1	1.010	-	-		QHG51846
OrthoDB	1	1.010	-	-		D1276923at2759
OrthoFinder	1	1.000	-	-		FOG0005716
OrthoInspector	1	1.000	-	-		oto98124
orthoMCL	1	0.900	-	-		OOG6_101398
Panther	1	1.100	-	-	LDO	PTHR10884
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4118
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770