DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Map2k5 and lic

DIOPT Version :9

Sequence 1:	XP_038936881.1	Gene:	Map2k5 / 29568	RGDID:	61890	Length:	487	Species:	Rattus norvegicus
Sequence 2:	NP_477162.1	Gene:	lic / 32257	FlyBaseID:	FBgn0261524	Length:	334	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	114/270 - (42%)
Similarity:	153/270 - (56%)	Gaps:	31/270 - (11%)

- Green bases have known domain annotations that are detailed below.

  Rat   172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEI-LYKCDSSYIIGFYGAFFVEN 235
            ||.|..|.|.|..|..:..:||||.|.:.:.:..|.:::.:|:| :...|..|.:.||||.:.|.
  Fly    52 LGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPYTVHFYGAMYREG 116

  Rat   236 RISICTEFMDGGSLD-VYRKI-------PEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLV 291
            .:.||.|.| ..||| .|.|:       .|.|||:||::||..|.||.: ||::||||||||:|:
  Fly   117 DVWICMEVM-STSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKVIHRDVKPSNILI 180

  Rat   292 NTSGQVKLCDFGVSTQLVNSIAKTY-VGTNAYMAPERISGE----QYGIHSDVWSLGISFMELAL 351
            |.:||||:||||:|..||:|||||. .|...|||||||..:    ||.|.||||||||..:|:|.
  Fly   181 NRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDVWSLGIGMIEMAT 245

  Rat   352 GRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPLGEFSEPFVHFITQWNRAGLCRTAHWSLETRP 416
            ||:||...:      .|.:.|:.:|::..|.||.|.||..|..||      .:|....:.  .||
  Fly   246 GRYPYDNWR------TPFEQLRQVVEDSPPRLPEGTFSPEFEDFI------AVCLQKEYM--ARP 296

  Rat   417 -YRFTLKKPF 425
             |...||..|
  Fly   297 NYEQLLKHSF 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Map2k5	XP_038936881.1	PB1_Map2k5	17..107	CDD:99717
Map2k5	XP_038936881.1	PKc_like	164..401	CDD:419665	107/243 (44%)
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	114/270 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920