Protein Alignment Hes2 and E(spl)m5-HLH

DIOPT Version :9

• Sequence 1: NP_062109.1
• Gene: Hes2 / 29567
• RGDID: 62082
• Length: 157
• Species: Rattus norvegicus
• Sequence 2: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Alignment Length: 165
• Identity: 50/165 - (30%)
• Similarity: 84/165 - (50%)
• Gaps: 28/165 - (16%)

  Rat    15 KSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASVCSTEA 79
            |..|||||::||||:|:.|..||.||....|.:.  ..:::||::||..:.|:|:|.....:..:
  Fly    20 KVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDA--ILRMDKAEMLEAALVFMRKQVVKQQAPVS 82

  Rat    80 PGSLDSYLEGYRACLARLARVLPACSVLEPAVSA---------------RLL--EHLRQRTVSGG 127
            |..:||:..||...::.::||: ||:   ||:|.               |:|  :.::....:..
  Fly    83 PLPMDSFKNGYMNAVSEISRVM-ACT---PAMSVDVGKTVMTHLGVEFQRMLQADQVQTSVTTST 143

  Rat   128 PPSLTPASA-----SAPAPSPPVPPPSSLGLWRPW 157
            |..|:|||:     :..:.|...|.|....:||||
  Fly   144 PRPLSPASSGYHSDNEDSQSAASPKPVEETMWRPW 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hes2	NP_062109.1	HLH	12..69	CDD:238036	22/53 (42%)
		ORANGE	84..128	CDD:128787	13/60 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		10/37 (27%)
		WRPW motif	154..157		2/2 (100%)
E(spl)m5-HLH	NP_524511.1	HLH	20..72	CDD:238036	22/53 (42%)
		ORANGE	87..131	CDD:128787	12/47 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334597
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47782
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850