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Protein Alignment Grik1 and GluRIIC

DIOPT Version :9

Sequence 1:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus
Sequence 2:	NP_608557.4	Gene:	GluRIIC / 33275	FlyBaseID:	FBgn0046113	Length:	940	Species:	Drosophila melanogaster

Alignment Length:	928	Identity:	274/928 - (29%)
Similarity:	458/928 - (49%)	Gaps:	117/928 - (12%)

- Green bases have known domain annotations that are detailed below.

  Rat    12 LWTR----DTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLM 72
            :|.|    ...|: .:|:|    ::..|.:.||..|...|.|    .|..|...|.:||...:
  Fly     1 MWQRILLLGCMWS-AFFMC----RSRGQQINIGAFFYDDELE----LEKEFMTVVNAINGPES-- 54

  Rat    73 PNTTLTYD-IQRINLFD-SFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRW 135
            ..|...|. |:|:...| |......|||.:..||||:||||..::...|..:||:..:|||:...
  Fly    55 EQTMRFYPLIKRLKPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDI 119

  Rat   136 KHPSVDS---RDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVY--EDSTGLIRLQELIKAPSR 195
            ....:.:   .....:||||..|.:|:|..|:|..:.|:..|:||  :|:....|||:|::....
  Fly   120 SDEGIQAEKPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAARLQDLLQLREV 184

  Rat   196 YNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTL 260
            :|..:::|:. ..:.|.:.:.|.::..:.  |:.||......|:|......|:..:|.|.|.|.|
  Fly   185 HNDVVRVRKF-HKDDDFRVMWKSIRGERR--VVLDCEPNMLVELLNSSTEFGLTGQYNHIFLTNL 246

  Rat   261 DLF-------ALDLELYRYSGVNMTGFRLL-NIDNPHVS----------SIIEKWSMERLQAPPR 307
            :.:       |.|.|.:   .||:|..||| |.|.|..|          :|:.:.|     .|||
  Fly   247 ETYTDHLEELAADNETF---AVNITAARLLVNPDPPPYSLPYGYVTQRDNIVYESS-----DPPR 303

  Rat   308 PETGLLDGMMTTEAALMYDAVYMVAIASHRAS-----QLTVSSLQC----HRHKPWRLGPRFMNL 363
                      |....|::||:.:.|.:...||     ::.|..:.|    ...:.|.:|.....|
  Fly   304 ----------TLIHDLIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRTWAMGRYLARL 358

  Rat   364 IKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVWKKIG--IWNSNSG 426
            :|     |.:|   .|.|     :|...|:...|:| ::.:..:  .:|.....||  ||:....
  Fly   359 MK-----GTSG---VNNT-----NFRTSILQFDEDG-QRITFNI--EVYDPLDGIGIAIWDPRGQ 407

  Rat   427 LNMTDGNRDRSNNITDSLANRTLI--VTTILEEPYVMYRKSDKP--LYGNDRFEGYCLDLLKELS 487
            :...:         .|..|.:.:|  |.|.:..||..|.::.:.  |.||..::||.:||:..::
  Fly   408 ITQLN---------VDVKAQKKMIYRVATRIGPPYFSYNETARELNLTGNALYQGYAVDLIDAIA 463

  Rat   488 NILGFLYDVKLVPDGKYG-AQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTL 551
            ..:||.|....|.|.:|| ...:..:|||::.|:|::.|.:.:..||||..|:..:||:.|||.|
  Fly   464 RHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQL 528

  Rat   552 GISIL-YRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSD 615
            |:||| |:.|: ....:.::|.|...::|:::|::...::.:..::||.:..:|.||||||.|.:
  Fly   529 GVSILAYKSPH-VEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCNRDPE 592

  Rat   616 VVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERME 680
            |:||.:.:.|:.|..|.::|..|.:::|::...|:....||.|.:||.:|||||||||||..:||
  Fly   593 VLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKME 657

  Rat   681 SPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLT 745
            ..|.:..||:.|.|:::|.:..|||......|..:.|...:..|::...||..|::.||:.||..
  Fly   658 GSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDDPSAYTKDNLEGVDRVRK 722

  Rat   746 T--DYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHM 808
            .  ||..|||:|::||..::||:|..:|.....|.|.:..|.|:.||..:::|||:|.|.|:|:.
  Fly   723 NRGDYMFLMETTTLEYHREQNCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYD 787

  Rat   809 MKEKWWR--GNGCPEEDSKEASA-LGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRKNNDVEQK 870
            :|:|||:  ...|.||...:|:. :..|.:.|||..|.||::::..:.|.|||..      |:|.
  Fly   788 LKQKWWKNPNASCFEEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVY------VQQV 846

  Rat   871 GKSSRLRF--YFRNKVRF 886
            ....||.|  .|:.::||
  Fly   847 ALEERLTFKDAFKKEIRF 864

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.