Protein Alignment Myh6 and Prm

DIOPT Version :10

• Sequence 1: NP_058935.2
• Gene: Myh6 / 29556
• RGDID: 62029
• Length: 1939
• Species: Rattus norvegicus
• Sequence 2: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 825
• Identity: 287/825 - (34%)
• Similarity: 495/825 - (60%)
• Gaps: 1/825 - (0%)

  Rat  1104 LQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKK 1168
            :|....|...:.:|..|:::||.||..|.::|:.::||:.::.::|||||||.|....|.|.|:|
  Fly    31 IQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRK 95

  Rat  1169 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1233
            |:||..|:|:.||:..|:.|.|...|:|||.:.:.:..||::.|.:.|.:.||:|::|:.|:.::
  Fly    96 RDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYEL 160

  Rat  1234 TSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA 1298
            .|.:|...|.|...||....||...:|..||:||..|::.|.::.|::|..||.||.:.:::.:.
  Fly   161 LSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKV 225

  Rat  1299 LISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVL 1363
            .:..::..|.....|:||.:|:||:|.:.::.|..:|.....:.|.:|.|.|||.||:.:|:|.|
  Fly   226 QLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQL 290

  Rat  1364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIE 1428
            .|||::...|:.|:.::...|.||:||.::|...|:.:.||.:|::..|.::|||.|.||.:|:|
  Fly   291 VKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVE 355

  Rat  1429 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
            .|::|:|:||.:...|.|.....:|...|.|.:.:|:....|:||::.::...:|.:..:..::.
  Fly   356 VLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKV 420

  Rat  1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEG 1558
            .::.....||||.|.:::.:....:.|..:.:||||...::||.|:.||.:|.:||||..:.||.
  Fly   421 KDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQ 485

  Rat  1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS-LDAETRSRNEALRVKKKMEG 1622
            :..|...:|||.:.:.||:|||||||:|..::.....::.|... ::||||.:.|..|:|||::.
  Fly   486 RGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQI 550

  Rat  1623 DLNEMEIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDAVRANDDLKENIAIVERRNTLLQAEL 1687
            .:.|:|:.|..||:...:.||.:|.....|.:.|...:|..|......:..|:.:||...|..||
  Fly   551 QITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGEL 615

  Rat  1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRN 1752
            ||:|:.::...|:::..|.:..|.:.|:..|.:.|.||::.|.|::.:||.:.::.||..:|.|.
  Fly   616 EEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRI 680

  Rat  1753 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKL 1817
            ::|:.:|...:...:.|::.:||:....||.:||::|..:|:|..||:|.|..|:.|.|:.:.||
  Fly   681 SDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKL 745

  Rat  1818 EARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKR 1882
            |||:|:||.|||.|::|:||::|.:||.||.:||:..|.|||:|||:.|||.:||...|:..|:|
  Fly   746 EARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRR 810

  Rat  1883 QAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
            |..|.|..:....::.|:.|.||:.||:|||.|||.:|.:|||.|
  Fly   811 QLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHR 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myh6	NP_058935.2	Myosin_N	32..76	CDD:460670
		MYSc_class_II	99..768	CDD:276951
		Actin-binding	657..679
		Actin-binding	759..773
		Calmodulin-binding. /evidence=ECO:0000250	790..807
		Calmodulin-binding. /evidence=ECO:0000250	816..833
		Myosin_tail_1	848..1925	CDD:460256	284/821 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1908..1939		13/20 (65%)
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	283/818 (35%)