Protein Alignment GSTT2 and GstO1

DIOPT Version :10

• Sequence 1: NP_000845.2
• Gene: GSTT2 / 2953
• HGNCID: 4642
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648237.1
• Gene: GstO1 / 38975
• FlyBaseID: FBgn0035907
• Length: 254
• Species: Drosophila melanogaster
• Alignment Length: 217
• Identity: 53/217 - (24%)
• Similarity: 75/217 - (34%)
• Gaps: 69/217 - (31%)

Human     3 LELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTL----KDGDFI 63
            :.|.||....|..|:||         .||        .|.:.|..::|..|:|.|    :.|:.:
  Fly    36 VHLVLDAKKIPYHAIYI---------NLR--------DKPEWFSLVSSSTKVPALELVKEQGNPV 83

Human    64 LTESSAILIYLSCKY-QTPDHWYPSDLQARAR-------------VHEYLGWHADCIRGTFGIPL 114
            |.||..|..||..|| :.|  .||.||..:|:             ...||..|.:        |.
  Fly    84 LIESLIICDYLDEKYPEVP--LYPKDLLKKAQEKILIERFGQFINAFYYLLLHDN--------PE 138

Human   115 WVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLM------ALEEL 173
            .:.......|:.|.:|:::|..|           ||.|      |....:.|.|      ..:.|
  Fly   139 QLVDTDHYAGLVVYEEELKRRCT-----------KFFG------GDSPGMLDYMMWPWCERFDSL 186

Human   174 MQPVALGYELFEGR-PRLAAWR 194
            .......:||...| |.|..||
  Fly   187 KYTFEQKFELSPERFPTLIKWR 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTT2	NP_000845.2	GST_N_Theta	3..78	CDD:239348	22/78 (28%)
		GST_C_Theta	91..216	CDD:198292	24/124 (19%)
GstO1	NP_648237.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..95	CDD:469754	21/75 (28%)
		GST_C_Omega	109..234	CDD:198293	24/125 (19%)