Protein Alignment GSTT2 and GstO3

DIOPT Version :10

• Sequence 1: NP_000845.2
• Gene: GSTT2 / 2953
• HGNCID: 4642
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648234.1
• Gene: GstO3 / 38972
• FlyBaseID: FBgn0035904
• Length: 241
• Species: Drosophila melanogaster
• Alignment Length: 199
• Identity: 46/199 - (23%)
• Similarity: 79/199 - (39%)
• Gaps: 38/199 - (19%)

Human    15 RAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTL----KDGDFILTESSAILIYLS 75
            ||..:...|| :|.....::|.:   |.:..::::.|.|:|.|    :.|:..|.||..|..||.
  Fly    35 RAHLVLNAKN-VPYHSVYINLTE---KPEWLVEVSPLLKVPALQLVAEKGEPSLIESLIIAEYLD 95

Human    76 CKYQTPDH-WYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAM 139
            .||  |:: ..|.|...||:         |.|.    :..:..:....|.:.|....:|...||:
  Fly    96 DKY--PENPLLPKDPLKRAQ---------DKIL----LERFSSITSAFINILVQGTGLEDYWTAL 145

Human   140 DQALQWLEDKFLGDR--PFLAGQQVTLADLM------ALEELMQPVALGYELFEGR-PRLAAWRG 195
            |     :.::.|..|  |:..|.:....|.|      .|..:...:...|...|.| |::..|..
  Fly   146 D-----IFEEELTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELKLQKEYNFNESRFPKITKWIA 205

Human   196 RVEA 199
            .::|
  Fly   206 LLKA 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTT2	NP_000845.2	GST_N_Theta	3..78	CDD:239348	18/66 (27%)
		GST_C_Theta	91..216	CDD:198292	23/118 (19%)
GstO3	NP_648234.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..95	CDD:469754	17/63 (27%)
		GST_C_Omega	109..230	CDD:198293	23/119 (19%)