Protein Alignment GSTT2 and GstE12

DIOPT Version :10

• Sequence 1: NP_000845.2
• Gene: GSTT2 / 2953
• HGNCID: 4642
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_611964.1
• Gene: GstE12 / 37960
• FlyBaseID: FBgn0027590
• Length: 223
• Species: Drosophila melanogaster
• Alignment Length: 211
• Identity: 69/211 - (32%)
• Similarity: 103/211 - (48%)
• Gaps: 31/211 - (14%)

Human     5 LFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSA 69
            |:...:|.|||||.:.||..|:.||||.::|:||:|.:.|||::|....:|||.||:..:.:|.|
  Fly     6 LYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATIIDSHA 70

Human    70 ILIYLSCKY-QTPDHWYPSDLQARARVHEYLGWHADC----IRGTFGIPLWVQVLGPLIGVQVPK 129
            |..||..|| |.....||.:|..||.|...|  |.|.    .|..|   |:..:|      ....
  Fly    71 ICAYLVEKYGQKEQQLYPKELVQRANVDARL--HLDSGHLFARLRF---LYEPIL------YYGS 124

Human   130 EKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQ-----PVALGYELFEGRPR 189
            .....::.|..|....:.:.||.|:|:|.|..:|:||..|:..:..     |:    :.|: .|:
  Fly   125 TDCSIDKIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPI----DEFK-FPK 184

Human   190 LAAWRGRVEAFLGAEL 205
            :.||..|:     |||
  Fly   185 MHAWLKRL-----AEL 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTT2	NP_000845.2	GST_N_Theta	3..78	CDD:239348	32/72 (44%)
		GST_C_Theta	91..216	CDD:198292	31/124 (25%)
GstE12	NP_611964.1	GST_N_Delta_Epsilon	4..77	CDD:239343	32/70 (46%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	31/125 (25%)