Protein Alignment GSTT2 and GstE8

DIOPT Version :10

• Sequence 1: NP_000845.2
• Gene: GSTT2 / 2953
• HGNCID: 4642
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_611330.2
• Gene: GstE8 / 37113
• FlyBaseID: FBgn0063492
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 221
• Identity: 62/221 - (28%)
• Similarity: 98/221 - (44%)
• Gaps: 29/221 - (13%)

Human    11 SQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLS 75
            |.|.||..:.....|||.|...::.:..:..|.|||:.|....:|||:|....:.:|.||..||.
  Fly    12 SPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFIWDSHAISAYLV 76

Human    76 CKYQTPDHWYPSDLQARARVHEYLGWHADC--IRGTFGIPLWVQVLGPLIG---VQVPKEKVERN 135
            .||...|..||.||..||.|.:.|.:.:..  :.|..||      ..||..   ..:|||:.:
  Fly    77 SKYGQSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGI------TKPLFATGQTTIPKERYD-- 133

Human   136 RTAMDQALQWLEDKFLGDRPFLAGQQVTLAD------LMALEELMQPVALGYELFEGRPRLAAWR 194
              |:.:...::| .||....|:||.|:|:||      :.||...:....:.|      ..:.||.
  Fly   134 --AVIEIYDFVE-TFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKY------ANITAWI 189

Human   195 GRVEAF-LGAELCQEAHSIILSILEQ 219
            .|:|.. ...|.|.:....::::|::
  Fly   190 KRIEELPYYEEACGKGARDLVTLLKK 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTT2	NP_000845.2	GST_N_Theta	3..78	CDD:239348	22/66 (33%)
		GST_C_Theta	91..216	CDD:198292	32/136 (24%)
GstE8	NP_611330.2	GstA	4..209	CDD:440390	61/213 (29%)