Protein Alignment GSTT2 and GstT4

DIOPT Version :10

• Sequence 1: NP_000845.2
• Gene: GSTT2 / 2953
• HGNCID: 4642
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_572886.2
• Gene: GstT4 / 32299
• FlyBaseID: FBgn0030484
• Length: 237
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 67/209 - (32%)
• Similarity: 105/209 - (50%)
• Gaps: 16/209 - (7%)

Human     3 LELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFL-QINSLGKLPTLKDGDFILTE 66
            |:.:.|.::|.|||:||..:.:.||.|...:.::||:|.:.||. .:|...|||.:.|..:.|:|
  Fly     5 LKFYFDFLNQSSRALYILLEASKIPFEAIPISMLKGEHLTGEFRDNVNRFRKLPAITDHGYQLSE 69

Human    67 SSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPL-------WVQVLGPLIG 124
            :.||..:|:.:...|:||||.....|:|:.|||.|.    :...|:..       |   |.|.:.
  Fly    70 NVAIFRHLAREKLVPEHWYPRRHLGRSRIDEYLAWQ----QTNMGVATTEYFQQKW---LVPYLQ 127

Human   125 VQVPKEK-VERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRP 188
            ...|.:. |......::..|...|..||..|.|:.|..::.|||.|:.|:.||.::||..|:.|.
  Fly   128 KTRPADNAVNLASKQLEHTLNEFEQLFLNSRKFMMGDNISYADLSAICEIDQPKSIGYNAFQNRN 192

Human   189 RLAAWRGRVEAFLG 202
            :||.|...|...||
  Fly   193 KLARWYETVREELG 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTT2	NP_000845.2	GST_N_Theta	3..78	CDD:239348	26/75 (35%)
		GST_C_Theta	91..216	CDD:198292	36/120 (30%)
GstT4	NP_572886.2	GST_N_Theta	5..80	CDD:239348	26/74 (35%)
		GST_C_Theta	95..220	CDD:198292	36/119 (30%)