Protein Alignment GSTT2 and GstT2

DIOPT Version :10

• Sequence 1: NP_000845.2
• Gene: GSTT2 / 2953
• HGNCID: 4642
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_724816.3
• Gene: GstT2 / 246386
• FlyBaseID: FBgn0050005
• Length: 228
• Species: Drosophila melanogaster
• Alignment Length: 238
• Identity: 70/238 - (29%)
• Similarity: 116/238 - (48%)
• Gaps: 35/238 - (14%)

Human     3 LELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTES 67
            :..:.||:|..:|.::|..|.:..|:|...:.|.|.:..:.|:.:||...|:|.:..|||.|:|:
  Fly     5 IRFYYDLLSPIARGLWIGLKFSNSPVEYCPIALRKFEQLTDEYKKINRFQKVPAIVGGDFHLSET 69

Human    68 SAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIR---GTFGIPLWVQVLGPLIGVQVPK 129
            .||:.||:.|.|..:..||..|:.||||.|:|.|....||   ..:....|   |.|:.|: .||
  Fly    70 IAIIRYLADKGQFDEKLYPKTLENRARVDEFLEWQHLNIRLACSMYFRDAW---LFPMNGI-APK 130

Human   130 EK----------VERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELF 184
            .|          ||.|...:::.  |||:      .||.|:.:|:||::...|:.|.....|.:.
  Fly   131 PKPEQIQALIEGVENNLGLLERL--WLEN------DFLVGKNLTMADILGSSEINQLRLCQYRVD 187

Human   185 EGR-PRLAAW--RGRVEAFLGAELCQEAHSIILSILEQAAKKT 224
            |.: |::..|  |.||.|       ...|...|:.:::.:|::
  Fly   188 EKKFPKVVKWLERVRVSA-------NPYHDEGLTFIDRKSKQS 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTT2	NP_000845.2	GST_N_Theta	3..78	CDD:239348	24/74 (32%)
		GST_C_Theta	91..216	CDD:198292	40/140 (29%)
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	24/74 (32%)
		GST_C_family	93..218	CDD:470672	40/143 (28%)