Protein Alignment Ptgs2 and cysu

DIOPT Version :10

• Sequence 1: NP_058928.3
• Gene: Ptgs2 / 29527
• RGDID: 620349
• Length: 604
• Species: Rattus norvegicus
• Sequence 2: NP_650627.1
• Gene: cysu / 42100
• FlyBaseID: FBgn0038511
• Length: 753
• Species: Drosophila melanogaster
• Alignment Length: 748
• Identity: 145/748 - (19%)
• Similarity: 241/748 - (32%)
• Gaps: 252/748 - (33%)

  Rat     1 MLFRAVLLCAALALSHAANPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFLTRIKL 65
            |:.|.:||..| |::||                     ||.       .:||...|........|
  Fly     1 MILRILLLSLA-AVAHA---------------------QYH-------QFGEQLQTAHGSDCALL 36

  Rat    66 LLKPTPNTVH-YILTHFKGVWNIVNNIP---FLRNSIMRYVLTSRSHLIDSPP------------ 114
            |..|..::|: |.:..|:|..|..||.|   ...::|....|.:|..:..:.|
  Fly    37 LAGPGRSSVYDYNVNLFRGTLNPYNNGPGTCITYDAINAAYLDARKRIHVAQPKSDWKPEELATV 101

  Rat   115 -------------TYNVHY---------------------------------GYKSWEAF-SNLS 132
                         ||.:.|                                 .|:.::.. :|:.
  Fly   102 GELLLDISIQLARTYGLSYEEIEKGLPTIDTSKTLIREVCPPFFAGVECRPGKYRRFDGLCNNIE 166

  Rat   133 Y---------YTRALPPV-ADDCPTP-MGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAF 186
            :         :.|.:.|: :|....| :.|.| ::||.|: |:.:.:...:...|..||.|:.|
  Fly   167 HPTWGAANAPFQRLIGPLYSDGINAPRISVTG-RDLPFSR-VVSRTMHPDDGFHDHAGTVMVIA- 228

  Rat   187 FAQHFTHQFFKTDQKRGP-----------------------------------------GFTRG- 209
            :.|...|.|..|.....|                                         .|.||
  Fly   229 WGQFMDHDFTLTGTPLDPINRNDPEECCKRPLHLKHPYCNEIRIPDDDYFYRLFNVKCIDFVRGF 293

  Rat   210 --------LGHG---------VDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQV 257
                    ||..         :|.|.|||.......|||....|.::..        |..::..:
  Fly   294 PSPRPGCKLGSRQQFNTLTGVIDANTVYGVKESFARKLRTGYGGLMRMN--------PVFQEYGL 350

  Rat   258 DMIYPPHVPEHLRFAVGQEVFGLV-PGLMMYA------------------TIWLREHNRVCDILK 303
            ..:.|      |:..:..|  |.. |...||.                  |:..|||||:...|.
  Fly   351 KDLLP------LKLDIPDE--GCTRPNKSMYCFEGGEIRVNEQLVLTCMHTLMAREHNRLATALA 407

  Rat   304 QEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFN 368
            |.:..||||.|||.:|.|.|.....:...:::..|.|.....||.   |..|:..|.:...|..|
  Fly   408 QINKHWDDETLFQEARRINIAIVQHVTFNEFLPILLGKEVMEKFG---LVLQKDGYWDGYDSTVN 469

  Rat   369 ----------TLYHWHPLLPDTFNIEDQEYTF---KQF---------LYNNSILLEH--GLAHFV 409
                      .....|.|||.......:.:.|   |:.         ||...:|.|:  ||.:.|
  Fly   470 PGIIDSFAGAAFRFGHSLLPTAVERWSKAHKFIASKRLSDLIRRPYDLYRAGVLDEYFMGLMNQV 534

  Rat   410 -----ESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTG 469
                 :|.|:::...:.........:..|: .::.:.||.......|:||...|....:::|:.|
  Fly   535 AQAMDDSITQEVTNHLFKKEGARFGMDLVS-FNMQRGREFGIPGYMEFRKFCGLPTSNTWDEMYG 598

  Rat   470 E--KEMAAELKALYHDIDAMELYPALLVEKPRPDAIFGET---MVELGAPFSLKGLMGNPICSPQ 529
            .  .|......:::.....::|:...:.||..|.::.|.|   ::.....:..:|        .:
  Fly   599 SMPNETVLRYGSIFEHPADIDLWSGGVSEKSLPGSMLGPTFACVIATQMSYLRRG--------DR 655

  Rat   530 YW-----KPSTFGGEVGFRIINTASIQSLICNN 557
            :|     :||:|..| ..:.|..|.:..|||:|
  Fly   656 FWYELPNQPSSFTPE-QLQEIRKAKLSRLICDN 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptgs2	NP_058928.3	EGF	21..53	CDD:394967	3/31 (10%)
		prostaglandin_endoperoxide_synthase	75..562	CDD:188648	128/674 (19%)
cysu	NP_650627.1	An_peroxidase	155..699	CDD:460804	114/565 (20%)