DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc22a6 and CG31103

DIOPT Version :9

Sequence 1:	NP_058920.1	Gene:	Slc22a6 / 29509	RGDID:	69338	Length:	551	Species:	Rattus norvegicus
Sequence 2:	NP_001097914.1	Gene:	CG31103 / 43030	FlyBaseID:	FBgn0051103	Length:	506	Species:	Drosophila melanogaster

Alignment Length:	437	Identity:	84/437 - (19%)
Similarity:	174/437 - (39%)	Gaps:	85/437 - (19%)

- Green bases have known domain annotations that are detailed below.

  Rat   142 MVGVLLGAMVFGYLADRLGRRKVLIL-NYLQTAVSGTCAAYAPNYTVYCVFRLLSGMSLA----- 200
            :.|:.|...::||::|.:|||:||:. |:...|:. ....:..:..::.:..||.|:|:.
  Fly    77 VTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQ-FVLMFVTSVWLFNIINLLVGISVGAVSAA 140

  Rat   201 --------------SIAINCMTLNVEWMPIHTRAYVGTLI--GYVYSLGQFLLAGIAYAVPHWRH 249
                          ::|||..|:.|....|:..|....::  .:..::|.|:..       .||.
  Fly   141 LYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFR-------PWRL 198

  Rat   250 LQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARIN-GKQ-------EEGAKLSI 306
            |.||..:|.||..:...::.||.::..|..:.:..:.|:..:::.| ||.       :|....|.
  Fly   199 LLLVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEFTLKSE 263

  Rat   307 EVLRTSLQKEL----TLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGL----------- 356
            :.:..:|..|.    .|||...:.:.|...|...:..|| ::..|...|:..|:
  Fly   264 DPVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILC-NLALFGMFFSSNGMQLWFPEIVNRS 327

  Rat   357 ---------VMDLQGFGVSM-----------------YLIQVIFGAVDLPAKFVCFLVINSMGRR 395
                     |.::....|..                 |:..::.|...|....:..|::|.:||:
  Fly   328 SGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQGLILNPLGRK 392

  Rat   396 PAQMASLLLAGIC-ILVNGIIPKSHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLG 459
            ...:|:|.:|.:. :|::.:...:..::...|.:|..|.   |.:.:.....:|.||.:|...:.
  Fly   393 NVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGL---SISIMIGAIVDLVPTHLRSKAVS 454

  Rat   460 MGSTMARVGSIVSP-LVSMTAEFYPSMPLFIFGAVPVVASAVTALLP 505
            ...::.|:|.|.:. |:.:..:.|.:....:|....:|...:...||
  Fly   455 FCMSLGRLGIIAATNLMGVMLQPYCNTTFAMFTCTLIVCIVIVHYLP 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a6	NP_058920.1	2A0119	11..515	CDD:273328	84/437 (19%)
		MFS	135..505	CDD:119392	82/435 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	514..551
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	79/409 (19%)
CG31103	NP_001097914.1	MFS	34..>189	CDD:119392	23/112 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346996
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840