Protein Alignment GSTP1 and GstS1

DIOPT Version :10

• Sequence 1: NP_000843.1
• Gene: GSTP1 / 2950
• HGNCID: 4638
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_001261040.1
• Gene: GstS1 / 36927
• FlyBaseID: FBgn0010226
• Length: 250
• Species: Drosophila melanogaster
• Alignment Length: 208
• Identity: 56/208 - (26%)
• Similarity: 96/208 - (46%)
• Gaps: 32/208 - (15%)

Human     4 YTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNT 68
            ||:.||.|:.....||.|.|...|.:::..||.:.|.  :||.:...||:|..:.....::||.:
  Fly    50 YTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWP--ALKPTMPMGQMPVLEVDGKRVHQSIS 112

Human    69 ILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVK----------AL 123
            :.|.|.:|:||.|....|...:|:|.|.:.|.|..  |..:.:||  .:|.:|          .:
  Fly   113 MARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLS--SEQFVSYE--PEDEIKEKKLVTLNAEVI 173

Human   124 PGQLKPFETLLSQNQG----GKTFIVGDQISFA---DYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181
            |..|:..|..:..|.|    ||  :....:.||   ||  ::.::..::|.|     :|.|...|
  Fly   174 PFYLEKLEQTVKDNDGHLALGK--LTWADVYFAGITDY--MNYMVKRDLLEP-----YPALRGVV 229

Human   182 GRLSARPKLKAFL 194
            ..::|...:||::
  Fly   230 DAVNALEPIKAWI 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTP1	NP_000843.1	GST_N_Pi	3..76	CDD:239374	22/71 (31%)
		GST_C_Pi	84..210	CDD:198319	30/128 (23%)
GstS1	NP_001261040.1	GST_N_Sigma_like	50..119	CDD:239337	22/70 (31%)
		GST_C_Sigma_like	129..232	CDD:198301	27/115 (23%)