DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgs4 and Axn

DIOPT Version :9

Sequence 1:	NP_058910.1	Gene:	Rgs4 / 29480	RGDID:	3567	Length:	205	Species:	Rattus norvegicus
Sequence 2:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster

Alignment Length:	210	Identity:	44/210 - (20%)
Similarity:	76/210 - (36%)	Gaps:	30/210 - (14%)

- Green bases have known domain annotations that are detailed below.

  Rat    21 HRLGFLLQKSDSC---------EHSSSHSKKDKVVTCQRVSQEEVKKWAESLENLINHECGLAAF 76
            |..|......:.|         |.|......:.|....:.|......||.:|.:|:....|:..|
  Fly     4 HPSGIRKHDDNECSGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELF 68

  Rat    77 KAFLKSE---YSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETS 138
            |.:::.|   |: ::::|:.:||..|:...|.|:    |:|...........::::....|.:..
  Fly    69 KKYVEEEAPAYN-DHLNFYFACEGLKQQTDPEKI----KQIIGAIYRFLRKSQLSISDDLRAQIK 128

  Rat   139 RNMLEPTIT----CFDEAQKKIFNLMEKDSYRRFLKSRFYLDLTNPSSCGAEK--QKGAKSSADC 197
            .....|.|.    .||..|:.:...:..:.|..||.|..|:......|...|:  ..||..|...
  Fly   129 AIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGSGSA 193

  Rat   198 -------TSLVPQCA 205
                   :||...||
  Fly   194 GSSGSGGSSLAGACA 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgs4	NP_058910.1	RGS_RGS4	63..176	CDD:188669	26/119 (22%)
Axn	NP_733336.1	RGS	55..170	CDD:295367	26/119 (22%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900