Protein Alignment Cd180 and Fili

DIOPT Version :10

• Sequence 1: NP_001099875.1
• Gene: Cd180 / 294706
• RGDID: 1308170
• Length: 662
• Species: Rattus norvegicus
• Sequence 2: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Alignment Length: 349
• Identity: 93/349 - (26%)
• Similarity: 145/349 - (41%)
• Gaps: 69/349 - (19%)

  Rat   351 LYIKGNTKRLELGSGCLETLE-------HLRELDLSHDDIETSDCCNLQLRNLSHLQSLNLSYNE 408
            :.:...||.:.|....:.|||       .|..||||.:.|||....|.:.:  |.|::||||.|.
  Fly    69 IQLNPETKYINLTVNRIRTLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQ--SELRTLNLSRNL 131

  Rat   409 PLGLRTEAFKECPQLELLDLAFTRLHVKDAQSPFQNLHLLKVLNLSHCLLGSSNQHLLDGLPALR 473
            ...|...|||....|.||||:|.|:.... .:...:|..|..|:|::..:.|...:...|:..|.
  Fly   132 VSSLHKHAFKGLTNLLLLDLSFNRIETVH-PTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLE 195

  Rat   474 HLNLQGNRF---PNGNIQKTNPLQAL----------------GSLEILILSFCD--LSSIDHQAF 517
            .|..:.||.   |..|:...:.|::|                |..|:|.||...  :|.:|..||
  Fly   196 VLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAF 260

  Rat   518 INLKIMNHVDLSHNRLTSSSIEALSHLKGI-YLNLASNRISIIPP--------------SLLPVL 567
            ..|..:.|:|||.|.||....:.||.|..: ||||..||.|.:|.              |.|..|
  Fly   261 EGLISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFL 325

  Rat   568 -----------SQQRTINLRQN------PLDCTCSNIYFLEWYKENMQKLEDIEDTFCANPPL-- 613
                       :..:|::|..|      |:.....|...||.|.::    ..::..:.|..|:
  Fly   326 QRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQS----NSLQTLYSAQFPVDQ 386

  Rat   614 LRGVKVSDVMLSCSMAAVGIFFLI 637
            |:.:.:.|..|.|:.:.:.::.|:
  Fly   387 LQKLYLGDNPLQCNCSLLWLWRLV 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cd180	NP_001099875.1	PRK15370	<44..>209	CDD:185268
		leucine-rich repeat	55..78	CDD:275380
		leucine-rich repeat	79..102	CDD:275380
		leucine-rich repeat	103..126	CDD:275380
		leucine-rich repeat	127..150	CDD:275380
		leucine-rich repeat	151..174	CDD:275380
		leucine-rich repeat	175..195	CDD:275380
		LRR	194..560	CDD:443914	74/237 (31%)
		leucine-rich repeat	196..223	CDD:275380
		leucine-rich repeat	224..244	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		leucine-rich repeat	301..323	CDD:275380
		leucine-rich repeat	324..347	CDD:275380
		leucine-rich repeat	348..372	CDD:275380	6/27 (22%)
		leucine-rich repeat	373..398	CDD:275380	9/24 (38%)
		leucine-rich repeat	399..422	CDD:275380	10/22 (45%)
		leucine-rich repeat	423..447	CDD:275380	8/23 (35%)
		leucine-rich repeat	448..471	CDD:275380	5/22 (23%)
		leucine-rich repeat	472..498	CDD:275380	8/44 (18%)
		leucine-rich repeat	499..522	CDD:275380	9/24 (38%)
		leucine-rich repeat	523..546	CDD:275380	10/22 (45%)
		PCC	550..>616	CDD:188093	20/98 (20%)
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	80/279 (29%)
		leucine-rich repeat	75..97	CDD:275378	6/21 (29%)
		leucine-rich repeat	98..121	CDD:275380	9/24 (38%)
		leucine-rich repeat	122..145	CDD:275380	10/22 (45%)
		leucine-rich repeat	146..169	CDD:275380	8/23 (35%)
		leucine-rich repeat	170..193	CDD:275380	5/22 (23%)
		leucine-rich repeat	194..217	CDD:275380	6/22 (27%)
		leucine-rich repeat	218..265	CDD:275380	12/46 (26%)
		leucine-rich repeat	266..289	CDD:275380	10/22 (45%)
		leucine-rich repeat	290..313	CDD:275380	8/22 (36%)
		leucine-rich repeat	314..338	CDD:275380	3/23 (13%)
		LRR_8	337..397	CDD:404697	12/63 (19%)
		leucine-rich repeat	339..360	CDD:275380	4/20 (20%)