Protein Alignment Pdia3 and CaBP1

DIOPT Version :9

• Sequence 1: NP_059015.2
• Gene: Pdia3 / 29468
• RGDID: 68430
• Length: 510
• Species: Rattus norvegicus
• Sequence 2: NP_001285979.1
• Gene: CaBP1 / 34976
• FlyBaseID: FBgn0025678
• Length: 433
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 111/500 - (22%)
• Similarity: 162/500 - (32%)
• Gaps: 241/500 - (48%)

  Rat    16 LASALL-------ASALLASASDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYE 73
            |||.||       .||..:.:..|:|||..||:..|....:  :.:|||:|||||||:.|.|||:
  Fly     4 LASILLLAFVVGSVSAFYSPSDGVVELTPSNFDREVLKDDA--IWVVEFYAPWCGHCQSLVPEYK 66

  Rat    74 AAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQA 137
            ..|..|||:|.:..|:..|::....::||.|:||:|||...:::.. |:|.|||..|.     :|
  Fly    67 KLAKALKGVVKVGSVNADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIA-----EA 126

  Rat   138 GPASVPLRTEDEFKKFISDKDASVVGFFRDLFSDGHSEFLKAASNLRDNYRFAHTNVESLVKEYD 202
            ..|        |.||    |...|:|      ..|.|                           .
  Fly   127 ALA--------EVKK----KVQGVLG------GGGGS---------------------------S 146

  Rat   203 DNGEGITIFRPLHLANKFEDKIVAYTEKKMTSGKIKKFIQESIFGLCPHMTEDNKDLIQGKDLLT 267
            ..|.|         ::..:|.|                          .:||||
  Fly   147 SGGSG---------SSSGDDVI--------------------------ELTEDN----------- 165

  Rat   268 AYYDVDYEKNTKGSNYWRNRVMMVAKTFLDAGHKLNFAVASRKTFSHELSDFGLESTTGEIPVVA 332
                                                                             
  Fly   166 ----------------------------------------------------------------- 165

  Rat   333 IRTAKGEKFVMQEEFSRDGKALERFLQEYFDGNLKRYLKSEPIPETNEGPVKVVVAESFDDIVNA 397
                                                                      ||.:|..
  Fly   166 ----------------------------------------------------------FDKLVLN 172

  Rat   398 EDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVKGFPTIYFS 461
            .|...|:||:||||||||||.|::.:..::|.  ..:.:..:||||: ...:.|.|:|:|||.|.
  Fly   173 SDDIWLVEFFAPWCGHCKNLAPEWAKAAKELK--GKVKLGALDATAHQSKAAEYNVRGYPTIKFF 235

  Rat   462 PANKKLT--PKKYEGGRELNDFISYL-QREATNPP------IIQE 497
            ||..|..  .::|:|||..:|.:|:. .:...|.|      ||.|
  Fly   236 PAGSKRASDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIINE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdia3	NP_059015.2	ER_PDI_fam	31..492	CDD:273457	99/465 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	489..510		4/14 (29%)
		Prevents secretion from ER	507..510
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	38/94 (40%)
		PDI_a_P5	157..262	CDD:239299	45/266 (17%)
		Thioredoxin_6	190..383	CDD:290560	29/92 (32%)
		P5_C	271..400	CDD:239281	2/9 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910