Protein Alignment GSTM1 and GstS1

DIOPT Version :10

• Sequence 1: NP_000552.2
• Gene: GSTM1 / 2944
• HGNCID: 4632
• Length: 218
• Species: Homo sapiens
• Sequence 2: NP_001261040.1
• Gene: GstS1 / 36927
• FlyBaseID: FBgn0010226
• Length: 250
• Species: Drosophila melanogaster
• Alignment Length: 226
• Identity: 61/226 - (26%)
• Similarity: 101/226 - (44%)
• Gaps: 52/226 - (23%)

Human     5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQW--LNEKFKLGLDFPNLPYL-IDG 66
            |.|::::.||..:|.|..|.:..||:.:.|        |.:|  |.....:|    .:|.| :||
  Fly    52 LFYFNVKALAEPLRYLFAYGNQEYEDVRVT--------RDEWPALKPTMPMG----QMPVLEVDG 104

Human    67 AHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQL-GMICYNPEFE--------- 121
             .::.||.::..::|:...|||.|..|.:::||:.:...|..:.. ..:.|.||.|
  Fly   105 -KRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLSSEQFVSYEPEDEIKEKKLVTL 168

Human   122 --KLKPKYLEELPEKLKLYSEF--LGKRPW----FAGNKITFVDFLVYDV-LDLHRIFEPKCLDA 177
              ::.|.|||:|.:.:|.....  |||..|    |||    ..|::.|.| .||        |:.
  Fly   169 NAEVIPFYLEKLEQTVKDNDGHLALGKLTWADVYFAG----ITDYMNYMVKRDL--------LEP 221

Human   178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208
            :|.|:..:.....||.|.|:::.     |||
  Fly   222 YPALRGVVDAVNALEPIKAWIEK-----RPV 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSTM1	NP_000552.2	GST_N_Mu	3..84	CDD:239373	21/81 (26%)
		GST_C_Mu	92..212	CDD:198318	36/136 (26%)
GstS1	NP_001261040.1	GST_N_Sigma_like	50..119	CDD:239337	20/79 (25%)
		GST_C_Sigma_like	129..232	CDD:198301	29/114 (25%)