DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Celf2 and bru3

DIOPT Version :9

Sequence 1:	XP_038951514.1	Gene:	Celf2 / 29428	RGDID:	68347	Length:	546	Species:	Rattus norvegicus
Sequence 2:	NP_001369050.1	Gene:	bru3 / 39527	FlyBaseID:	FBgn0264001	Length:	552	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	189/438 - (43%)
Similarity:	249/438 - (56%)	Gaps:	81/438 - (18%)

- Green bases have known domain annotations that are detailed below.

  Rat   140 MHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAF 204
            |:..:|:|||::|..:...|||||:||:||:..|:|:|.:|.|||.||||.|||||||.|:||||
  Fly    21 MNRALQLKPAENESRSEHLDRKLFVGMLSKQQTEDDVRQIFHPFGTIEECTILRGPDGASKGCAF 85

  Rat   205 VTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLT 269
            |.|.::..||:||..:|.||||.|.||.:|||:|||:|:::.||: ||:|..|..||...:...
  Fly    86 VKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRM-QQMAGHMNLLNPFVFNQF- 148

  Rat   270 GLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLS 334
                               |..||::           |.|..|.|.||||.|..|| :...||::
  Fly   149 -------------------SPYGAYA-----------QQQQQAALMAAAATAPGSA-AAYMNPMA 182

  Rat   335 STSSAL----------GALTSP------VAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNIN 383
            :.::.:          .:|.||      :.|:|||...|.|..:..:.....|:.
  Fly   183 ALATQIPHGLNGTGQPPSLPSPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVF---------- 237

  Rat   384 ALAGTISIAQMLSGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYS---QSLL 445
                |..|.|.......|:..:...||.||.|.|   |..|:.|:..:...|.|.:|.   |:|.
  Fly   238 ----TNGIPQTAFPGHPLHLTIPPQGLPNGDAAT---LQHAFPGLPPFPGVAFPAVYGQFPQALP 295

  Rat   446 QQQSA-AGSQKE-----------GPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQT 498
            ...:| |.:|:|           ||||.|||||||||||||.:::|||:|||||||:|||||:.|
  Fly   296 PPLAAVAPTQREDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRAT 360

  Rat   499 NLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 546
            |.||||||||:|||.|||||||||||||||||||||||||.|:.|:||
  Fly   361 NQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPY 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Celf2	XP_038951514.1	RRM1_CELF1_2_Bruno	67..150	CDD:410040	4/9 (44%)
		RRM2_CELF1_2	159..239	CDD:410042	49/79 (62%)
		RRM3_CELF1_2	454..545	CDD:241082	74/101 (73%)
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	49/79 (62%)
		ELAV_HUD_SF	43..404	CDD:273741	177/410 (43%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	65/77 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54704
OrthoDB	1	1.010	-	-		D1209165at2759
OrthoFinder	1	1.000	-	-		FOG0000286
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X208
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930