Protein Alignment Kcnv2 and Shawl

DIOPT Version :10

• Sequence 1: NP_001099840.1
• Gene: Kcnv2 / 294065
• RGDID: 1309271
• Length: 561
• Species: Rattus norvegicus
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 131/545 - (24%)
• Similarity: 212/545 - (38%)
• Gaps: 157/545 - (28%)

  Rat   108 VNVGGHSYQLECCELANYPKTRLGRLVTSTSRNCQLGLCDDYEAKTDEYFFDRDPAVFQLIYNFY 172
            :||.|..|:.....|...|.|||.||..:.:         :|:...:||||||.|.||..|.|:|
  Fly     9 LNVSGIRYETYKATLKKIPATRLSRLTEALA---------NYDPVLNEYFFDRHPGVFTQILNYY 64

  Rat   173 TSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRD-----ELSEQLKIQRELRAQAQ 232
            .:|.|....::|...|.|||.:||:.......||...:...||     .:.::|.|:.|   :..
  Fly    65 RTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENE---KPT 126

  Rat   233 AEEAEELF--------RDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVASNLFVLISVVALALNT- 288
            .|:...||        .::..:...:.::|.:.::|.||..||.:...|..|:.:||::..|.|
  Fly   127 EEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTH 191

  Rat   289 ------VEEMQHQAE-QGTGG-------------------------------------------- 302
                  :....|.|. .|.||
  Fly   192 PGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSG 256

  Rat   303 ------------------------------------------------------GDPRPILEHVE 313
                                                                  |.|.....:||
  Fly   257 NFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVE 321

  Rat   314 MLCVAFFTLEFLLRLASTPNLRRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHGKGSPREHD 378
            ::|..:|.:|.::||..:|||.:|.:|.:|::|..|.|.||
  Fly   322 LVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY------------------------ 362

  Rat   379 LETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSA 443
            .:.:.|:|:...:|....::||.|:.||.|||.|||....|.:...:::..|:.|:.:||..|::
  Fly   363 TDVMQRMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFAS 427

  Rat   444 AVYSVE--HDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPIS 506
            ..|..|  .|.|...|.||....|||.|:::||||||:.|:|:.|.....||...|::...:|:.
  Fly   428 LAYYAEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVP 492

  Rat   507 ILYNKFSDYYSKLKAYEYTAIRRER 531
            ::.:.||.:||..:|......:|.|
  Fly   493 VIVSNFSMFYSHTQARSKLPKKRRR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcnv2	NP_001099840.1	BTB_POZ	106..213	CDD:453885	35/104 (34%)
		Ion_trans	275..520	CDD:459842	78/352 (22%)
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	37/114 (32%)
		Ion_trans	307..506	CDD:459842	68/222 (31%)