DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phkg1 and CaMKI

DIOPT Version :9

Sequence 1:	NP_113761.1	Gene:	Phkg1 / 29353	RGDID:	3325	Length:	388	Species:	Rattus norvegicus
Sequence 2:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	286	Identity:	103/286 - (36%)
Similarity:	155/286 - (54%)	Gaps:	33/286 - (11%)

- Green bases have known domain annotations that are detailed below.

  Rat    18 ENYEPKEILGRGVSSVVRRCIHKPTCQE-YAVKIIDITGGGSFSSEEVQELREATLKEVDILQKV 81
            |.|....:||.|..|.||....|.:..| :||||||        .:.::...|:...|:.:|::.
  Fly    29 EKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIID--------KKALKGKEESLENEIRVLRRF 85

  Rat    82 SG--------------HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMR 132
            |.              ||||:||.:|||..:..:||.:|:..|||||.:.||.:.|||:...::|
  Fly    86 SANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIR 150

  Rat   133 ALLEVVCTLHKLNIVHRDLKPENILL---DDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPE 194
            .:||.|..:|:..:|||||||||:|.   ||:..|.::|||.| :::....:...||||.|:|||
  Fly   151 QILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLS-KMEDSGIMATACGTPGYVAPE 214

  Rat   195 IIQCSMDEGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSD 259
            ::      ....|||.||:||.|||.|.||.|.|||:......:...|:.|.::|.||.||:.|:
  Fly   215 VL------AQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISE 273

  Rat   260 TVKDLVSRFLVVQPQDRCSAEEALAH 285
            :.|..:...:.|..:.|.:.::||.|
  Fly   274 SAKHFIKNLMCVTVEKRYTCKQALGH 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phkg1	NP_113761.1	PKc_like	16..291	CDD:419665	103/286 (36%)
		Calmodulin-binding (domain-N)	303..327
		Calmodulin-binding (domain-C)	343..367
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	103/286 (36%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	102/284 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920