Protein Alignment GSK3B and Pk34A

DIOPT Version :10

• Sequence 1: NP_002084.2
• Gene: GSK3B / 2932
• HGNCID: 4617
• Length: 433
• Species: Homo sapiens
• Sequence 2: NP_609603.1
• Gene: Pk34A / 34705
• FlyBaseID: FBgn0028410
• Length: 392
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 141/367 - (38%)
• Similarity: 201/367 - (54%)
• Gaps: 27/367 - (7%)

Human    39 TVVATPGQGP--DRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIM 101
            :|::|...|.  ..|..|......:||:||||.||||.:.:|.|:||:|:.|.:.:....|.:||
  Fly    25 SVISTYAVGRLCSEPALVRIEVKDLIGSGSFGRVYQAHVNESEEIVAVKQTLYNPKLSQGEAEIM 89

Human   102 RKL-DHCNIVRLRYFFYSS---GEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLP-VIYVKLY 161
            .:| ||.|||||  ..:||   |....: |:.||::|:|.|:.....::....|... :|.|::.
  Fly    90 GQLKDHNNIVRL--IMHSSVSLGFPSVD-YVLLVMEYMPMTLLDYINYHLTVLQPAERLINVRIL 151

Human   162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPE 226
            .||:||.|.|:|..||.|||:||:|||:|....||||.||||||.||..||::||||||.|||||
  Fly   152 SYQMFRGLGYLHLLGISHRDVKPENLLIDNQKMVLKLSDFGSAKLLVPQEPSISYICSRLYRAPE 216

Human   227 LIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDS-GVDQLVEIIKVLGTPTREQIREMNPNYTE 290
            |..|...|:.::|:|||||||||||.|.|:|.... ...||..|:.:|||...|:..|:......
  Fly   217 LFAGYELYSCAVDIWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGTDGLERAPEILSKCGN 281

Human   291 FKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE 355
            ...|:.....|.             .:.....|.:...|.:....|...||::|:.||:|..:||
  Fly   282 SLHPRTTRPSWN-------------YLLNTAVPQDLCGLLNSCFIYEAAARISPMMACSHGSYDE 333

Human   356 LRDPN---VKLPNGRDTPALFNFTTQELSSNPPLATILIPPH 394
            ||..:   :.:|||...|.||:|.:.|:.::|.|...|:|.|
  Fly   334 LRIMDAMALPMPNGNPLPPLFDFNSLEMGTDPKLWVNLLPIH 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GSK3B	NP_002084.2	STKc_GSK3	51..356	CDD:271039	122/310 (39%)
Pk34A	NP_609603.1	STKc_GSK3	39..334	CDD:271039	122/310 (39%)