DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GSK3B and gskt

DIOPT Version :10

Sequence 1:NP_002084.2 Gene:GSK3B / 2932 HGNCID:4617 Length:433 Species:Homo sapiens
Sequence 2:NP_733426.1 Gene:gskt / 318552 FlyBaseID:FBgn0046332 Length:501 Species:Drosophila melanogaster


Alignment Length:405 Identity:252/405 - (62%)
Similarity:312/405 - (77%) Gaps:23/405 - (5%)


- Green bases have known domain annotations that are detailed below.


Human    35 SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQ 99
            :||||||||...|.|...|:||||.||:||||||||:|||:..|.|:|||||||||:||||||||
  Fly    12 NKVTTVVATNAFGADVMSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQ 76

Human   100 IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQ 164
            |||||.|.||:.|::||:|||||:||||||||::::|||:|:|.|.|:||||||||.:|:|||||
  Fly    77 IMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQ 141

Human   165 LFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIF 229
            |.||:.|:||.|.|||||||||:|||.:|.|||||||||||||:.||||||||||||||||||||
  Fly   142 LLRSMGYLHSLGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIF 206

Human   230 GATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFP 294
            |:||||:.||:||||||::||||||.||||||||||:|||:||:||||.||:.:|||:|.:||.|
  Fly   207 GSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLP 271

Human   295 QIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELR-D 358
            ::|.|||:|             |||.|||.|||.|.|::|.|:|.||::||..|||.|||||| |
  Fly   272 ELKPHPWSK-------------VFRIRTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQD 323

Human   359 PNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANT-GDRG--- 419
            |:.:|||||..|.|||||..|.:..|....:|:|   |.|.:::|...:.|..:.|| |:..   
  Fly   324 PHQQLPNGRSLPPLFNFTDYEKTIEPDTMPLLLP---RAQGSSTTKEPSAAHRNRNTAGEESPRK 385

Human   420 --QTNNAASASASNS 432
              .:...|:|:.|.|
  Fly   386 TEDSQKPATAALSKS 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GSK3BNP_002084.2 STKc_GSK3 51..356 CDD:271039 211/304 (69%)
gsktNP_733426.1 STKc_GSK3 30..320 CDD:271039 211/302 (70%)

Return to query results.
Submit another query.