DRSC/TRiP Functional Genomics Resources

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Protein Alignment GSK3B and sgg

DIOPT Version :10

Sequence 1:NP_002084.2 Gene:GSK3B / 2932 HGNCID:4617 Length:433 Species:Homo sapiens
Sequence 2:NP_001259193.1 Gene:sgg / 31248 FlyBaseID:FBgn0003371 Length:1168 Species:Drosophila melanogaster


Alignment Length:403 Identity:300/403 - (74%)
Similarity:334/403 - (82%) Gaps:27/403 - (6%)


- Green bases have known domain annotations that are detailed below.


Human    32 KDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR 96
            :||||:||||||||||.||.|||||||||||||||||||:||||||:||||||||||||:|||||
  Fly   623 RDGSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNR 687

Human    97 ELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLY 161
            ||||||||:|||||:|.|||||||||:|||:|||||:|:|||||:|||.|::.|||:|:.:::||
  Fly   688 ELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLY 752

Human   162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPE 226
            |||||||||||||.||||||||||||||||:|||||||||||||||:.|||||||||||||||||
  Fly   753 MYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPE 817

Human   227 LIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEF 291
            |||||.:||:.|||||||||||||||||||||||||||||||:||||||||||||||||||||||
  Fly   818 LIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEF 882

Human   292 KFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDEL 356
            ||||||:|||.|             |||.|||.|||.|.|.||||||:||:|||:||||.|||||
  Fly   883 KFPQIKSHPWQK-------------VFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDEL 934

Human   357 R-DPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQ 420
            | :.|..||||||.|.|||||..|||..|.|...|:|.|.:         ||:...    |:|..
  Fly   935 RMEGNHTLPNGRDMPPLFNFTEHELSIQPSLVPQLLPKHLQ---------NASGPG----GNRPS 986

Human   421 TNNAASASASNST 433
            ...|||.:||.||
  Fly   987 AGGAASIAASGST 999

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GSK3BNP_002084.2 STKc_GSK3 51..356 CDD:271039 249/304 (82%)
sggNP_001259193.1 STKc_GSK3 643..934 CDD:271039 249/303 (82%)

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