Protein Alignment SLC25A6 and colt

DIOPT Version :10

• Sequence 1: NP_001627.2
• Gene: SLC25A6 / 293
• HGNCID: 10992
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_477221.1
• Gene: colt / 33470
• FlyBaseID: FBgn0019830
• Length: 306
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 73/291 - (25%)
• Similarity: 130/291 - (44%)
• Gaps: 31/291 - (10%)

Human     2 TEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQ--YKGIVDCIVRIPKE 64
            ||:..:..|.||.||.....:..:..|::.:|:.||..   .:.|..:|  |:|..||..:..|.
  Fly     9 TERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTM---PRPAPGEQPLYRGTFDCAAKTIKN 70

Human    65 QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129
            :||...::|..|.:....|..|:.||.....|::...|.|....:.:.|    .:|..:|..|..
  Fly    71 EGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQQRGEDAKLTYPQIF----VAGSFSGLFSTL 131

Human   130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGV 194
            .:.|.:..:..|....|:.| ||::.|:.||..|:.|..|:|.:::|...::...:.....||.|
  Fly   132 IMAPGERIKVLLQTQQGQGG-ERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLV 195

Human   195 YDTAKGMLPDPKNTHIVVSWMIAQTVTA--VAG----VVSYPFDTVRRRMMMQSGRKGADIMYTG 253
            |:..:.:......|..:.:   |.|:.|  |||    ::..|.|.::.|  :||..:|.   |..
  Fly   196 YEALQDVAKSKSETGQIST---ASTIFAGGVAGMAYWILGMPADVLKSR--LQSAPEGT---YKH 252

Human   254 TVDCWRKIFRD----EGGKAFFKGAWSNVLR 280
            .:   |.:|:|    :|..|.::|....:||
  Fly   253 GI---RSVFKDLIVKDGPLALYRGVTPIMLR 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A6	NP_001627.2	PTZ00169	3..298	CDD:240302	72/290 (25%)
		Solcar 1	6..98		25/93 (27%)
		Solcar 2	111..201		22/89 (25%)
		Solcar 3	212..297		21/79 (27%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	235..240		1/4 (25%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		1/4 (25%)
colt	NP_477221.1	Mito_carr	12..107	CDD:395101	25/97 (26%)
		Mito_carr	112..202	CDD:395101	22/94 (23%)
		Mito_carr	210..299	CDD:395101	21/82 (26%)