Protein Alignment Acvr2a and put

DIOPT Version :10

• Sequence 1: XP_063139269.1
• Gene: Acvr2a / 29263
• RGDID: 70911
• Length: 521
• Species: Rattus norvegicus
• Sequence 2: NP_001262575.1
• Gene: put / 41772
• FlyBaseID: FBgn0003169
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 532
• Identity: 246/532 - (46%)
• Similarity: 329/532 - (61%)
• Gaps: 45/532 - (8%)

  Rat     5 AKLAFAVFLISCSSGAILGRSETQECLFFNANW-ERDRTNQTGVEPCYGDKDKRRHCFATW--KN 66
            |:|.....||......:.|.....||..|:... ...:..:|.:|.|..:.||...|:..|  ..
  Fly    11 AQLTLVCCLIGIHGSILPGSHGIIECEHFDEKMCNTTQQCETRIEHCKMEADKFPSCYVLWSVNE 75

  Rat    67 ISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPE--VYFCCCEGNMCNEKFSYFPE---------M 120
            .:|.:.|..:||:.|...| ::|:|:...:..:  ::||||:|:.||....|...         .
  Fly    76 TTGILRIKMKGCFTDMHEC-NQTECVTSAEPRQGNIHFCCCKGSRCNSNQKYIKSTTEATTQVPK 139

  Rat   121 EVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQHAFHIMIED 185
            |.||..||.:.   .|....::|:  ||:|.|:   ...:||..|.|         |...|...:
  Fly   140 EKTQDGSNLIY---IYIGTSVFSV--LMVIVGM---GLLLYRRRKQA---------HFNEIPTHE 187

  Rat   186 PGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMK 250
            ......||||..:|:||||.||.||||.||:|:|.|:.||||||.:|:|:||..|:::|.||.|:
  Fly   188 AEITNSSPLLSNRPIQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMR 252

  Rat   251 HENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHED 314
            |.|||:|:|.||.   :| .:.|||:.:...|||.|:||::.:||.|||.|||:||.|||:|||:
  Fly   253 HPNILEFLGVEKH---MDKPEYWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEE 314

  Rat   315 IPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEV 378
            ||..| ||.||:|:|||.||||||||::|||||||||||:.|:.||..|||||||||||||||||
  Fly   315 IPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEV 379

  Rat   379 LEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHK 443
            |||||||.||||||||:||.||||||:.|||..| |||.|:.||||.|:|..|||:::||.||.|
  Fly   380 LEGAINFNRDAFLRIDVYACGLVLWEMVSRCDFA-GPVGEFQLPFEAELGLRPSLDEVQESVVMK 443

  Rat   444 KKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTM 508
            |.||.|.:.|:.|.|:.:.|:|:|||||||||||||:.||.||..|:.:..   :|:   .::..
  Fly   444 KLRPRLLNSWRAHPGLNVFCDTMEECWDHDAEARLSSSCVMERFAQLNKYP---STQ---LLIKN 502

  Rat   509 VTNVDFPPKESS 520
            .||:| ..|||:
  Fly   503 HTNID-DAKEST 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acvr2a	XP_063139269.1	None
put	NP_001262575.1	TFP_LU_ECD_ACVR2	33..125	CDD:467135	25/92 (27%)
		STKc_ACVR2	206..493	CDD:270955	183/290 (63%)