DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sell and hig

DIOPT Version :9

Sequence 1:	XP_038946544.1	Gene:	Sell / 29259	RGDID:	3655	Length:	460	Species:	Rattus norvegicus
Sequence 2:	NP_724773.1	Gene:	hig / 35949	FlyBaseID:	FBgn0010114	Length:	958	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	94/449 - (20%)
Similarity:	137/449 - (30%)	Gaps:	175/449 - (38%)

- Green bases have known domain annotations that are detailed below.

  Rat     9 GWRNER--KQALL----VTLGTFFLSAAHPPCARAQR--------------------PRCRRLRP 47
            |||..|  |..||    :.:| :.|...|...||.|.                    ||.....|
  Fly   536 GWRKTRLSKSTLLSNTEINVG-WDLPHGHSLQARCQELGIYKLLGESRVLCSNGLWAPRMPSCVP 599

  Rat    48 AEGLTEETQQA------MVFPWRCQSAQRGSWSFLKLWIWTLLCCDLLPHHGT---HC------- 96
            ...||..::.:      .:|        .||.||....:..      :|.|.|   .|
  Fly   600 TTVLTNYSEDSAPSIRIKIF--------NGSHSFEPSGVMA------VPPHSTVLMDCMYPRVRG 650

  Rat    97 -----WTYHYSERSMNWENARKFCKHNYTDLVAIQNKREIEYLEKTLPKNPTYYWIGIRKIGKTW 156
                 ||..|.:.|..|..|              |.::.:.|
  Fly   651 TPEWSWTSWYMQYSTGWSPA--------------QEEKAVRY----------------------- 678

  Rat   157 TWVGTNKTLTKEAENWGTGEPNNKKSKEDCVEIYIKRERDSGKWNDDACHKRK------AALCYT 215
                  :...|..||                       .|||.:   .|...:      |.:..|
  Fly   679 ------RLSIKNIEN-----------------------NDSGTF---TCTSPRGLTNSIAVVVAT 711

  Rat   216 ASCQPE-----------------SCNRHGECVETIN-----NNTCICDPGYYG--PQCQYVIQCE 256
            ::| |:                 ....|.||.|...     |.||:....:..  |.| :.|||.
  Fly   712 STC-PQLTEPLAPLKLRLEGNKLGQRAHYECPEGFRLDGAWNATCLASGNWSSPTPTC-HAIQCP 774

  Rat   257 PLKA--PELGTMNCIHPLGDFSFQSQCAFNCSEGSELLGNAKTECGASGNWTYLEPICQVIQCMP 319
            .|:.  |.|..:..     :.|...:..|.|..|.:|.|.|:.:|..||.|:...|.|:||||:.
  Fly   775 RLELDDPHLSLIEL-----NTSAWGRAVFKCQWGFKLTGPAQLDCEPSGVWSGPVPRCKVIQCVM 834

  Rat   320 LAAP---DLGTMECSHPLANFSFTSACTFTCSEETDLIGERKTVCRSSGSWSSPSPICQ 375
            ..||   .:|....|.  ...:..:..||:|::...|:||...:|..:|.||...|.|:
  Fly   835 PVAPLNGRIGGTSLSQ--RRLTVGALVTFSCNDGHSLVGESSIICTENGQWSHSPPFCK 891

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sell	XP_038946544.1	CLECT_selectins_like	97..215	CDD:153062	16/123 (13%)
		EGF_CA	218..250	CDD:238011	10/55 (18%)
		CCP	255..313	CDD:153056	16/59 (27%)
		PHA02817	275..>384	CDD:165167	33/104 (32%)
hig	NP_724773.1	PHA02927	705..952	CDD:222943	52/196 (27%)
		CCP	714..768	CDD:153056	10/54 (19%)
		CCP	<795..828	CDD:153056	11/32 (34%)
		CCP	832..891	CDD:153056	16/60 (27%)
		Sushi	894..952	CDD:278512
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I11952
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100