DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment F10 and CG11836

DIOPT Version :9

Sequence 1:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus
Sequence 2:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	100/275 - (36%)
Similarity:	151/275 - (54%)	Gaps:	29/275 - (10%)

- Green bases have known domain annotations that are detailed below.

  Rat   212 SELLNLNKTEPEAN----------------SDDVIRIVGGQECKRGECPWQALLFSDEETDGFCG 260
            |....|:.||.|..                |::.||||||:.....:.||.|.:..|.:.  .||
  Fly    61 SNAFGLSDTEDEVEYTENSSLKNCDCDCGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKF--HCG 123

  Rat   261 GTILNEFYILTAAHCLHQAKRFKVRV--GDLNTEQEDGGEMVHE-VDMIIKHNKFQRDTYDFDIA 322
            |::|.:.|:|:||||:.:.::.|:||  ||.:.|.....:.:.. |..:|||..|..|||:.|||
  Fly   124 GSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIA 188

  Rat   323 MLRLKTPITFRENVAPACLPQKDWAEATLMTQKTGIVSGFGRTHEKGRQSKVLKMMEVPYVDRNT 387
            :|||:.||:|.:.:.|.|||:.::..|    .:.|.|.|:|||.|.|....::..::||.:....
  Fly   189 LLRLRKPISFSKIIKPICLPRYNYDPA----GRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITE 249

  Rat   388 CRLS--TSFSITQNMFCAGYDAKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIY 450
            ||..  .|..||.:|.|||..:.  |:||||||||.:......||:.||||||.||.|:|..|:|
  Fly   250 CRNQRYKSTRITSSMLCAGRPSM--DSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVY 312

  Rat   451 TKVTAFLKWIDRSMK 465
            ::|:.|:.||..:::
  Fly   313 SRVSKFIPWIKSNLE 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372
		Tryp_SPc	232..462	CDD:238113	92/234 (39%)
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	92/235 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I3777
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H30976
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12321
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910