Protein Alignment PDIA3 and CaBP1

DIOPT Version :9

• Sequence 1: NP_005304.3
• Gene: PDIA3 / 2923
• HGNCID: 4606
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001285979.1
• Gene: CaBP1 / 34976
• FlyBaseID: FBgn0025678
• Length: 433
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 106/497 - (21%)
• Similarity: 168/497 - (33%)
• Gaps: 238/497 - (47%)

Human     3 LRRLALFPGVALLLA------AARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCK 61
            :|:||..    ||||      :|..:.:..|:|||..||:..:....:  :.:|||:|||||||:
  Fly     1 MRQLASI----LLLAFVVGSVSAFYSPSDGVVELTPSNFDREVLKDDA--IWVVEFYAPWCGHCQ 59

Human    62 RLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIV 125
            .|.|||:..|..|||:|.:..|:..|::....::||.|:||:|||...:::.. |:|.|||..|.
  Fly    60 SLVPEYKKLAKALKGVVKVGSVNADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIA 124

Human   126 SHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVE 190
                                       :|::
  Fly   125 ---------------------------EAAL---------------------------------- 128

Human   191 SLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLI 255
                                                   .::||.:|..:.|
  Fly   129 ---------------------------------------AEVKKKVQGVLGG------------- 141

Human   256 QGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTA 320
                             ..||                                   |..|..|::
  Fly   142 -----------------GGGS-----------------------------------SSGGSGSSS 154

Human   321 GEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAEN 385
            |:..:               |.:.|                                       |
  Fly   155 GDDVI---------------ELTED---------------------------------------N 165

Human   386 FDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAN-DVPSPYEVRG 449
            ||::|.|.:...|:||:||||||||||.|::.:..::|.  ..:.:..:||||: ...:.|.|||
  Fly   166 FDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELK--GKVKLGALDATAHQSKAAEYNVRG 228

Human   450 FPTIYFSPANKK--LNPKKYEGGRELSDFISYL-QREATNPP 488
            :|||.|.||..|  .:.::|:|||..||.:|:. .:...|.|
  Fly   229 YPTIKFFPAGSKRASDAQEYDGGRTASDIVSWASDKHVANVP 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PDIA3	NP_005304.3	YbbN	25..487	CDD:331940	96/466 (21%)
		ER retention motif	502..505
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	37/94 (39%)
		PDI_a_P5	157..262	CDD:239299	44/160 (28%)
		Thioredoxin_6	190..383	CDD:290560	29/83 (35%)
		P5_C	271..400	CDD:239281	106/497 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910