Protein Alignment SLC25A5 and Bmcp

DIOPT Version :10

• Sequence 1: NP_001143.2
• Gene: SLC25A5 / 292
• HGNCID: 10991
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_648501.1
• Gene: Bmcp / 39322
• FlyBaseID: FBgn0036199
• Length: 303
• Species: Drosophila melanogaster
• Alignment Length: 310
• Identity: 87/310 - (28%)
• Similarity: 142/310 - (45%)
• Gaps: 36/310 - (11%)

Human    10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQ-HASKQITADKQYKGIIDCVVRIPKEQGVLSFWRG 73
            :.|:.||||:..::....||:..|..||:| ....|..:..:|:|:.|..|:|.:|:|:.:.:.|
  Fly     8 RPFVYGGVASITAEFGTFPIDTTKTRLQIQGQKIDQSFSQLRYRGMTDAFVKISREEGLRALYSG 72

Human    74 NLANVIRYFPTQALNFAFKDKYKQI-----FLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYP 133
            ....|:|......:.|......|::     .|...|...:.|    .|:....||||.|.....|
  Fly    73 IWPAVLRQATYGTIKFGTYYTLKKLANERGLLINEDGSERVW----SNILCAAAAGAISSAIANP 133

Human   134 LDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTA 198
            .|..:.|:... ||.    :.:||..|..:|||.:|::||::|...:.|..::..:....:||..
  Fly   134 TDVLKVRMQVH-GKG----QHKGLLGCFGEIYKYEGVRGLWRGVGPTAQRAVVIASVELPVYDFC 193

Human   199 KGMLPDPKNTHI---VISWMIAQTVTAVAGLTSYPFDTVRRRMMMQ-------SG---RKGTDIM 250
            |..|.:....|:   .||..||...:|:|   |.|.|.:|.|:|.|       :|   ...|..:
  Fly   194 KLQLMNAFGDHVGNHFISSFIASLGSAIA---STPIDVIRTRLMNQRPVSITMNGVVTAAATPKL 255

Human   251 YTGTLDCWRKIARDEGGKAFFKG---AWSNVLRGMGGAFVLVLYDEIKKY 297
            |:|:|||..:..|:||..|.:||   .|  |..|.......:.|:::|||
  Fly   256 YSGSLDCAVQTIRNEGLPALYKGFIPTW--VRMGPWNIIFFITYEQLKKY 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A5	NP_001143.2	Solcar 1	6..98		24/88 (27%)
		PTZ00169	7..296	CDD:240302	84/307 (27%)
		Solcar 2	111..201		25/89 (28%)
		Solcar 3	212..297		31/97 (32%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	235..240		2/4 (50%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		2/4 (50%)
Bmcp	NP_648501.1	Mito_carr	7..97	CDD:395101	24/88 (27%)
		Mito_carr	<132..199	CDD:395101	20/71 (28%)
		Mito_carr	204..303	CDD:395101	32/103 (31%)