DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Chka and eas

DIOPT Version :9

Sequence 1:	XP_006230769.1	Gene:	Chka / 29194	RGDID:	61944	Length:	463	Species:	Rattus norvegicus
Sequence 2:	NP_523364.2	Gene:	eas / 32585	FlyBaseID:	FBgn0000536	Length:	495	Species:	Drosophila melanogaster

Alignment Length:	473	Identity:	116/473 - (24%)
Similarity:	184/473 - (38%)	Gaps:	165/473 - (34%)

- Green bases have known domain annotations that are detailed below.

  Rat    78 QPEPRTRRRAYLWCKEFLP------GAWRGLRE---------DQFHISV--IRGGLSNMLFQCSL 125
            :||.::|:.|.:   .|:|      ...:|.:|         |..|:..  ...|::|.|..| .
  Fly    83 KPEDKSRKEAIV---PFVPIFVEEADVIQGAKELLKVIRPTWDLSHVEFKSFTDGITNKLVGC-F 143

  Rat   126 PDSIASVGDE------PRK-----------------------------------------VLLRL 143
            ...|:.:.||      |.|                                         ||:|:
  Fly   144 HKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDDRAADDGSPVQYSDNVVLVRI 208

  Rat   144 YGAILKMVFLIKLWNGKRSCNKEGSEQAQNENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQ 208
            ||.  |...||             ..:|:.:|              |.:|....|.|.||..|..
  Fly   209 YGN--KTDLLI-------------DRKAETQN--------------FLLLHTYGLAPSLYATFKN 244

  Rat   209 GRLEQFIPSRRLDTEELCLPDISAEIAEKMATFH-------------GMKMPFNKEPKWLFGTME 260
            |.:.:::|...|:|:.:..|:|...:|.:||..|             .|.|.:.|...:|....|
  Fly   245 GLVYEYVPGTTLNTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLVPE 309

  Rat   261 KYLNQVLRLKFSREARVQQLHKFLSYNLPL-----ELENLRSLLQYTRSPVVFCHNDCQEGNILL 320
            ::.:.      .:..||::..      ||:     |...|...|:...||:||.|||...||::.
  Fly   310 RFSDA------EKHKRVKETF------LPIGRLREEFNKLYEYLEALDSPIVFSHNDLLLGNVIY 362

  Rat   321 LEGQENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWM----YDYTYEKYPFFRANIQKYPTRKQQ 381
            .:....     :..||:||:.||::.|||||||.|..    .||:            :||.|:.|
  Fly   363 TQSLNT-----VNFIDYEYADYNFQAFDIGNHFAEMCGVDEVDYS------------RYPKREFQ 410

  Rat   382 LHFISSYL------TTFQNDFESLSSEEQSATKEDMLLEVNRFALASHFLWGLWSIVQAKISSIE 440
            |.::..||      :..|||...|           :.::||:||||||..|.:||::||:.|:|:
  Fly   411 LQWLRVYLEEYLQRSNIQNDEVEL-----------LYVQVNQFALASHIFWTVWSLLQAEHSTID 464

  Rat   441 FGYMEYAQARFDAYFDQK 458
            |.|:.||..|::.|..:|
  Fly   465 FDYVGYAFLRYNEYLARK 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chka	XP_006230769.1	PLN02236	95..461	CDD:177880	111/456 (24%)
Chka	XP_006230769.1	ChoK_euk	107..458	CDD:270705	106/427 (25%)
eas	NP_523364.2	ETNK_euk	126..478	CDD:270706	104/421 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000493
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810