Protein Alignment Cd36 and dsb

DIOPT Version :10

• Sequence 1: NP_113749.2
• Gene: Cd36 / 29184
• RGDID: 2301
• Length: 472
• Species: Rattus norvegicus
• Sequence 2: NP_001097477.1
• Gene: dsb / 38252
• FlyBaseID: FBgn0035290
• Length: 615
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 127/481 - (26%)
• Similarity: 223/481 - (46%)
• Gaps: 60/481 - (12%)

  Rat    14 VIGAVLAVFGGIL--MPVGDLLIEKTIKREVVLEEGTIAFKNWVKTGTTVYRQFWIFDVQNPEEV 76
            :||.:..:.|.||  ||..|..|.|.::    |...|:::..|.:.|.....:.:|::|.||:..
  Fly    84 IIGIITLILGIILSSMPWLDYFILKNLR----LWNDTLSYHYWQRPGVIRLTKLYIYNVTNPDGF 144

  Rat    77 AKNSSKIKVKQRGPYTYRVRYLAKENITQDPKDSTVSFVQPNGAIFEPSLSVGTE----NDNFTV 137
            .: ..|..:::.||:.|| ..:.|.|:.....:.|||:.......|.|.||:..:    ..|..:
  Fly   145 LR-GEKPHLQEVGPFVYR-EDMQKVNVKFHENNYTVSYQHKKILQFVPELSIDKDTPITTPNIPL 207

  Rat   138 LNLAVAAAPHIYTNSFVQGVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVP--YP----IST 196
            |.| .:.:|.:  ...:...::.::..::...|...:.::|.:||.|..:||..  ||    ...
  Fly   208 LTL-TSLSPKL--GYLLSKTISVVVTAAQFKPFINVTAEQLAFGYDDALVSLAHRFYPKHMRPME 269

  Rat   197 TVGVFYPYNNTVDGVYKVFNGKDNISKVAIIDTYKGKRNLSYW-ESYCDMINGTDAASFPP-FVE 259
            .:|:....|.|:..|..|..|.|::.:...||...|..:|.:| |..|..|.|::.:.||| .:.
  Fly   270 RMGLLLGRNGTLTEVSSVKTGMDSMDQFGYIDQLNGLDHLPHWSEPPCTSIAGSEGSFFPPRELT 334

  Rat   260 KSRTLRFFSSDICRSIYAVFGSEVNLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTS 324
            ||..:..:..|:||.|...:...:...||....|.||.|::.....||:|.|:.|        :.
  Fly   335 KSEVVHIYDKDLCRIIPLKYVESLEKDGIAADLFRLPNNSYGDSAHNPENKCYDT--------SE 391

  Rat   325 Y----GVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLNPNEDEHRTYLDVEPITGFTLQFAK 385
            |    |:.:|..|:.|.|||||.|||..:.||:...:|||.|..::|.||..::|..|..|:...
  Fly   392 YEPIQGLQNISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPEREKHETYFKIQPKLGVPLEGKV 456

  Rat   386 RLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFRNQVTGKIK---LLGLV--- 444
            |:|:|:.|..|:.:..:::. |.::.|::||.| |.          :::|..||   .||.|
  Fly   457 RIQLNLKVTRAKDVYPVRDF-RDFVFPVMWLEE-GI----------SELTPAIKRWIYLGTVIAP 509

  Rat   445 -------EMVLLGVGVVMFVAFMISY 463
                   .:::||....:..:|:.:|
  Fly   510 SAVPIGSYLMILGGAFAIIFSFVRAY 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cd36	NP_113749.2	CD36	14..463	CDD:460076	126/479 (26%)
		Required for interaction with thrombospondins, THBS1 and THBS2. /evidence=ECO:0000250	93..120		7/26 (27%)
		Interaction with PTK2, PXN and LYN. /evidence=ECO:0000250|UniProtKB:P16671	460..472		1/4 (25%)
dsb	NP_001097477.1	CD36	103..534	CDD:460076	119/459 (26%)