Protein Alignment CD274 and si:ch211-241b2.5

DIOPT Version :9

• Sequence 1: NP_054862.1
• Gene: CD274 / 29126
• HGNCID: 17635
• Length: 290
• Species: Homo sapiens
• Sequence 2: XP_009293364.2
• Gene: si:ch211-241b2.5 / 100536137
• ZFINID: ZDB-GENE-081104-192
• Length: 760
• Species: Danio rerio
• Alignment Length: 314
• Identity: 85/314 - (27%)
• Similarity: 145/314 - (46%)
• Gaps: 35/314 - (11%)

Human     1 MRIFAVFIFMT-YWH--LLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWE---- 58
            |:...|.||.. .|.  |..:|||.||:..|..|...::.:||.|...|:  .:.:.|.|.
Zfish   267 MKRTLVIIFQALLWPAVLSASFTVNVPRSTYEAELNGDVRLECVFSALKR--SSDITVIWSRVHP 329

Human    59 MEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADY 123
            ..|.||.....|:|......|::.:||:|:...|....|.|.:..::::|:|.|:|::.....||
Zfish   330 KPDVNIYWLDKGKEIHNHTSSAFHKRAQLISHLLRENRAVLHLKKLRIKDSGTYQCIVEGDEVDY 394

Human   124 KRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREE 188
            |:||:.|.||::.:.:.:....  ..|.||:|:::|:|.|:|.|:......|:..:.|:.|..:|
Zfish   395 KQITLNVTAPFSPVRKSLRKAG--EDEVELSCESQGFPSAQVYWSDGQKLNLTLFSNTSVSSTDE 457

Human   189 KLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIP-ELPLAHPPNERTHLVILGAILLCLG 252
            .|..:.|.|::.......:.||| .:..|...||...|| |:||    :.....|.:||:::.|
Zfish   458 DLILIVSKLKVERELVNNYTCTF-IVKGEIQQTATFSIPEEIPL----HGSALFVWIGAVIVVL- 516

Human   253 VALTFIFRL-------RKGRMMDVKKCGIQDTNSK----------KQSDTHLEE 289
            :|:.||..:       :|.|..:..||......|.          .::.||..|
Zfish   517 LAVIFISIILHRRKYGQKNRRNEASKCAYLFPQSSSVNTDSLLTVNENRTHARE 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CD274	NP_054862.1	Ig	54..117	CDD:325142	18/66 (27%)
		Ig	135..220	CDD:325142	20/84 (24%)
si:ch211-241b2.5	XP_009293364.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8560
Inparanoid	1	1.050	104	1.000	Inparanoid score	I12189
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006437
OrthoInspector	1	1.000	-	-		otm28715
orthoMCL	1	0.900	-	-		OOG6_119058
Panther	1	1.100	-	-	LDO	PTHR25466
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.960