Protein Alignment PYCARD and Pycard

DIOPT Version :9

• Sequence 1: NP_037390.2
• Gene: PYCARD / 29108
• HGNCID: 16608
• Length: 195
• Species: Homo sapiens
• Sequence 2: NP_075747.3
• Gene: Pycard / 66824
• MGIID: 1931465
• Length: 193
• Species: Mus musculus
• Alignment Length: 195
• Identity: 140/195 - (71%)
• Similarity: 159/195 - (81%)
• Gaps: 2/195 - (1%)

Human     1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYG 65
            |||||||||||||||:.:||||||:|||:|.||||||||||||||.|||:||||||||:|||:||
Mouse     1 MGRARDAILDALENLSGDELKKFKMKLLTVQLREGYGRIPRGALLQMDAIDLTDKLVSYYLESYG 65

Human    66 AELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVE 130
            .|||..|||||||||:|.||| .|.:.|||..|....|.||.|:.| ||:||||.|||||||.|:
Mouse    66 LELTMTVLRDMGLQELAEQLQ-TTKEESGAVAAAASVPAQSTARTG-HFVDQHRQALIARVTEVD 128

Human   131 WLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS 195
            .:||||:|.|||:.||||||||.|:..||||||||.|:||.||||.|||||:|...|||.|||:|
Mouse   129 GVLDALHGSVLTEGQYQAVRAETTSQDKMRKLFSFVPSWNLTCKDSLLQALKEIHPYLVMDLEQS 193

Human   196  195
            Mouse   194  193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PYCARD	NP_037390.2	Pyrin_ASC-like	5..86	CDD:260033	65/80 (81%)
		CARD_ASC_NALP1	113..193	CDD:260039	56/79 (71%)
Pycard	NP_075747.3	Pyrin_ASC-like	5..86	CDD:260033	65/80 (81%)
		CARD_ASC_NALP1	111..191	CDD:260039	56/79 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83953022
Domainoid	1	1.000	124	1.000	Domainoid score	I39479
eggNOG	1	0.900	-	-		E1_2CYBZ
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8307
Inparanoid	1	1.050	267	1.000	Inparanoid score	I15507
Isobase	1	0.950	-	0	Normalized mean entropy	S9765
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG41811
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002022
OrthoInspector	1	1.000	-	-		oto113997
orthoMCL	1	0.900	-	-		OOG6_114527
Panther	1	1.100	-	-	LDO	PTHR10454
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7505
SonicParanoid	1	1.000	-	-		X3863
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	17.240