Protein Alignment SLC25A4 and slc25a4

DIOPT Version :10

• Sequence 1: NP_001142.2
• Gene: SLC25A4 / 291
• HGNCID: 10990
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_988909.1
• Gene: slc25a4 / 394504
• XenbaseID: XB-GENE-1001646
• Length: 298
• Species: Xenopus tropicalis
• Alignment Length: 298
• Identity: 267/298 - (89%)
• Similarity: 284/298 - (95%)
• Gaps: 0/298 - (0%)

Human     1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 65
            |.|...||||||||||:|||:|||||||||||||||||||||||||.:||||||:||||||||||
 Frog     1 MSDQVLSFLKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQISVDKQYKGIMDCVVRIPKEQ 65

Human    66 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCF 130
            ||:|||||||||||||||||||||||||||||:||||||:||||||:|.||||||||||||||||
 Frog    66 GFISFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHKQFWRFFVGNLASGGAAGATSLCF 130

Human   131 VYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVY 195
            ||||||||||||||||||..:|||.|||:||.||:|.|||:||||||||||||||||||||||||
 Frog   131 VYPLDFARTRLAADVGKGLNEREFTGLGNCIAKIYKLDGLKGLYQGFNVSVQGIIIYRAAYFGVY 195

Human   196 DTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRK 260
            ||||||:||||||||.|||||||:||||||||||||||||||||||||||||||||.||:|||:|
 Frog   196 DTAKGMMPDPKNVHIVVSWMIAQTVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYKGTIDCWKK 260

Human   261 IAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298
            |:||||.|||||||||||||||||||||||||||||||
 Frog   261 ISKDEGPKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A4	NP_001142.2	Solcar 1	6..98		84/91 (92%)
		PTZ00169	7..298	CDD:240302	263/290 (91%)
		Solcar 2	111..201		78/89 (88%)
		Solcar 3	212..297		78/84 (93%)
		Important for transport activity. /evidence=ECO:0000269|PubMed:27693233	235..240		4/4 (100%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		4/4 (100%)
slc25a4	NP_988909.1	PTZ00169	2..298	CDD:240302	264/295 (89%)