Protein Alignment SLC25A4 and slc25a4

DIOPT Version :10

• Sequence 1: NP_001142.2
• Gene: SLC25A4 / 291
• HGNCID: 10990
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_999867.1
• Gene: slc25a4 / 327067
• ZFINID: ZDB-GENE-030131-5275
• Length: 298
• Species: Danio rerio
• Alignment Length: 297
• Identity: 264/297 - (88%)
• Similarity: 283/297 - (95%)
• Gaps: 0/297 - (0%)

Human     1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 65
            |.|.|.||||||||||||||:||||||||||||||||||||||||:|:.||||||||||||||||
Zfish     1 MSDAAISFLKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADMQYKGIIDCVVRIPKEQ 65

Human    66 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCF 130
            |||||||||||||||||||||||||||||||::||||||::.|||||||||||||||||||||||
Zfish    66 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKKIFLGGVDKNTQFWRYFAGNLASGGAAGATSLCF 130

Human   131 VYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVY 195
            ||||||||||||||:|||||:|||.|||:|:.||||||||||||.||||||||||||||||||:|
Zfish   131 VYPLDFARTRLAADIGKGAAEREFTGLGNCVAKIFKSDGLRGLYLGFNVSVQGIIIYRAAYFGIY 195

Human   196 DTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRK 260
            |||||||||||:.||.|||||||:||||||::||||||||||||||||||||||||.||:|||:|
Zfish   196 DTAKGMLPDPKHTHIVVSWMIAQTVTAVAGIISYPFDTVRRRMMMQSGRKGADIMYKGTIDCWKK 260

Human   261 IAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297
            ||||||.|||||||.|||:||.|||||||||||||||
Zfish   261 IAKDEGGKAFFKGALSNVIRGAGGAFVLVLYDEIKKY 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A4	NP_001142.2	Solcar 1	6..98		86/91 (95%)
		PTZ00169	7..298	CDD:240302	261/291 (90%)
		Solcar 2	111..201		81/89 (91%)
		Solcar 3	212..297		74/84 (88%)
		Important for transport activity. /evidence=ECO:0000269|PubMed:27693233	235..240		4/4 (100%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		4/4 (100%)
slc25a4	NP_999867.1	PTZ00169	7..296	CDD:240302	258/288 (90%)