Protein Alignment GRIK5 and Ir7d

DIOPT Version :9

• Sequence 1: XP_011525167.1
• Gene: GRIK5 / 2901
• HGNCID: 4583
• Length: 982
• Species: Homo sapiens
• Sequence 2: NP_001138175.1
• Gene: Ir7d / 7354416
• FlyBaseID: FBgn0259190
• Length: 594
• Species: Drosophila melanogaster
• Alignment Length: 446
• Identity: 91/446 - (20%)
• Similarity: 159/446 - (35%)
• Gaps: 122/446 - (27%)

Human   426 PYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVE-DGLYGAPE-PNGSWTGMVGEL 488
            ||:  |.|:::....:..:|....:||.:|..:.|..:|...| :||.|... .||::||.. ::
  Fly   221 PYM--RINWKSSDPMDGLDGLDGLLLRIVARKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAY-KM 282

Human   489 INRQKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSF---LDPFSPAVWLF 550
            :..::|::.:.....|.||...::.:.|:..:.    |.:.:..:.||..:   |.||....||.
  Fly   283 LRERRANITIGCAACTPERSTFLEATSPYSQMS----YIIVLQARGGYSIYEVMLFPFEKYTWLL 343

Human   551 MLLAYLAVSCVL----FLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEI 611
            :       |.:|    .:.:|     |..|.|.|..
  Fly   344 L-------STILGLHWIVGSR-----WRMPSPILAG----------------------------- 367

Human   612 MPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQT---NIEYGTIHAG 673
                         |..:..:|.:||.|::..|:    ...||:.:....||.   ...:.|.||.
  Fly   368 -------------WMLWIFVIRASYEASVFNFI----QNSPVKPSPRTLDQALSGGFRFITDHAS 415

Human   674 STMTF----FQNSRYQTYQRMWNYMQSKQP-SVF---VKSTEEGIARVLNSRYAFLLESTMNEYH 730
            ..||.    ||..         ..:.:.|| .||   :|:..:  .....|| |||.:..:.  |
  Fly   416 YRMTLKIPSFQGK---------TLISAGQPVDVFDALLKAPWK--TGAFTSR-AFLADHLVR--H 466

Human   731 RRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQE----NNRLEILKRKWWE------ 785
            |:....|..:...:......:..|.||.|..||...:..::.    .:..:||.   |:
  Fly   467 RKHRNQLVILAEKIVDNMLCMYFPHGSYFAWEINKLLFNMRSFGIFQHHSQILA---WDNLPTTT 528

Human   786 -----GGRCPKEEDHRAKGLGMENIGGIFIVLIC---GLIIAVFVAVMEFIWSTRR 833
                 |.|.....:..|.|.. |::..:...|.|   .|.|::.|..:|.: |.||
  Fly   529 DTDTPGKRIHSSTESVATGFA-ESMSFVVAALNCLMGALCISIVVFGLELL-SRRR 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GRIK5	XP_011525167.1	PBP1_iGluR_Kainate_KA1_2	25..399	CDD:107389
		ANF_receptor	42..379	CDD:279440
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:304360	76/382 (20%)
		Lig_chan	546..816	CDD:278489	55/302 (18%)
Ir7d	NP_001138175.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910