Protein Alignment GRIK5 and Ir7b

DIOPT Version :9

• Sequence 1: XP_011525167.1
• Gene: GRIK5 / 2901
• HGNCID: 4583
• Length: 982
• Species: Homo sapiens
• Sequence 2: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 777
• Identity: 145/777 - (18%)
• Similarity: 231/777 - (29%)
• Gaps: 325/777 - (41%)

Human   186 ETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLILRKASE--------------LGMT 236
            :||.:....:|:.....|:|:.|..:  :|:..|.....|:|:::.|              |...
  Fly    43 KTLYIYTHTNSQSTGGHLEELLDQVL--MIVPNNLQARRLLLQQSMEYKPYVHAVLALVDGLPSL 105

Human   237 SAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWREN-CEASTYLGP 300
            ||.|..|..|.|.           |..::..||  .:..:..|...:|...||.: ......|.|
  Fly   106 SAIYARIRATQDL-----------SHTLIYMSM--PTDAYGEEMQATLRFLWRLSVLNVGVVLRP 157

Human   301 ALSAALM-----FDAVH--VVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGL 358
            .....||     |.|:|  .|:|| ..:||.| :|.|..|  |.:.:|
  Fly   158 PGDHILMVSYFPFSALHGCQVISA-NVVNRYQ-VGTKRWA--SQDYFP----------------- 201

Human   359 TGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTIL 423
                                       .::|.:|.  .|...||..|:
  Fly   202 ---------------------------SKLGNFYG--CLLTCATWEDM----------------- 220

Human   424 ENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSW------- 481
              ||::.||:     |:..|.|....:|:.:||.|.|..       |||        |
  Fly   221 --PYLVWRPD-----GSGSFVGIEGALLQFMAENLNFTV-------GLY--------WMNKEEVL 263

Human   482 -----TGMVGELINRQKADLAVAAFTITAEREKVIDFSKP---FMT--LGISILYRVHMGRKPGY 536
                 :|.:.:.|....||.::..|.........|.:|:.   ||:  :.::.|...:    ..|
  Fly   264 ATFDESGRIFDEIFGHHADFSLGGFHFKPSAGSEIPYSQSTYYFMSHIMLVTNLQSAY----SAY 324

Human   537 FSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQY------TLGN 595
            .....||:|.:|..:.|..:....:|.|..|     |.:.|...|       |.|      |:|.
  Fly   325 EKLSFPFTPLLWRAIGLVLILACLLLMLLVR-----WRHHHELPR-------NPYYELLVLTMGG 377

Human   596 SL---WFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTAN------------------ 639
            :|   |             :|:...:|.|...|...||::.|.|.:.
  Fly   378 NLEDRW-------------VPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTIS 429

Human   640 --LAAFLTVQRMEV-----------------------PVESADDLADQ----------TNIEY-- 667
              ||...|:|..||                       .::|...||.|          |..||
  Fly   430 EVLAQHFTIQLAEVNEARILASLPELRPEQLVYLEGSELQSFPALAQQSGSSARVAILTPYEYFG 494

Human   668 --GTIHAGSTMTFFQNSRYQT-----YQRMWNYM-------------------QSKQPSVFVKST 706
              ..:|..|........|..|     |.|..:::                   .::|....|...
  Fly   495 YFRKVHPMSRRLHLVRERIYTQQLAFYVRRHSHLVGVLNKQIQHAHTHGFLEHWTRQYVSAVDEK 559

Human   707 EEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQ 771
            :|.:||:.::.|     ||::                      ||.   |.|...|
  Fly   560 DESVARIASTSY-----STLD----------------------GID---GDPSLSE--------- 585

Human   772 ENNRLEILKRKWWEGGRCPKEEDH-----RAKGLGMENIGGIFIVLICGLIIAVFVAVMEFI 828
                               .|||.     |...|.|..:..:|.:::...:.||.|.|:|.:
  Fly   586 -------------------SEEDQQVAPVRQNVLSMRELAALFWLILWANLGAVVVFVLELL 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GRIK5	XP_011525167.1	PBP1_iGluR_Kainate_KA1_2	25..399	CDD:107389	46/234 (20%)
		ANF_receptor	42..379	CDD:279440	43/214 (20%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:304360	84/477 (18%)
		Lig_chan	546..816	CDD:278489	61/364 (17%)
Ir7b	NP_572410.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156265
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840