Protein Alignment KLF15 and Spps

DIOPT Version :10

• Sequence 1: XP_011511045.1
• Gene: KLF15 / 28999
• HGNCID: 14536
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_001262902.1
• Gene: Spps / 42882
• FlyBaseID: FBgn0039169
• Length: 985
• Species: Drosophila melanogaster
• Alignment Length: 402
• Identity: 112/402 - (27%)
• Similarity: 158/402 - (39%)
• Gaps: 121/402 - (30%)

Human   142 PEFPLGDPDDVPRPFQ-PTLEEIEEFLEENMEPGVKEVPEGNSKDL---------DACSQLSAGP 196
            |..|...|..||.|.| |.|:.:.   .:|: ||:.:|...::..|         ...:||.
  Fly   465 PTAPTPAPAGVPTPMQMPNLQALP---IQNI-PGLGQVQIIHANQLPPNLPANFQQVLTQLP--- 522

Human   197 HKSHLHPGSSGRERCSP-----------------PP---GGASA-GGAQGPGGGPTPDGP----- 235
             .||....:.|:.:..|                 ||   |..|| |....|...|....|
  Fly   523 -MSHPQVQTQGQVQVMPKQEPQSPTQMITSIKQEPPDTFGPISATGNPPAPASTPNTASPQQQQI 586

Human   236 --------------IPVLLQIQPVPVKQESGTGPASPGQ-------------------------- 260
                          ||..:||..:|  |::...|.:|..
  Fly   587 KFLHTESNSLSSLSIPASIQITALP--QQATNTPNTPATTQPIPVSLPARSKVNAVTTSSTQITI 649

Human   261 APENVKVAQLLVNIQGQTFALVPQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMG 325
            ||...:|..:....:|.|.::......::.:..||:......:.:|:  ||....| |..|...|
  Fly   650 APTGGQVVSVTTQARGATASIRSTNTSTTTITTPSQSHLNMNISVAS--VGGAATG-GGGGTATG 711

Human   326 QKFPK--------------NPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPG 376
            :..|:              ...::..:.|.|...||.|:|.|:|||:||||.||||:||.|:|..
  Fly   712 EPKPRLKRVACTCPNCTDGEKHSDKKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAF 776

Human   377 CGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSS------------- 428
            ||.||:|||||.||||:|:|.|.:||..|.|||.||||||||||.|...||.
  Fly   777 CGKRFTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDHLSKHIKTHFKSRSGVELIELSIKQETK 841

Human   429 -----RSVRSVN 435
                 :|:.:||
  Fly   842 GGNAPKSISTVN 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLF15	XP_011511045.1	KLF15_N	22..340	CDD:410206	52/287 (18%)
		SFP1	<325..420	CDD:227516	54/108 (50%)
		C2H2 Zn finger	342..364	CDD:275368	13/21 (62%)
		C2H2 Zn finger	372..394	CDD:275368	15/21 (71%)
		zf-H2C2_2	386..411	CDD:463886	15/24 (63%)
		C2H2 Zn finger	402..422	CDD:275368	15/19 (79%)
Spps	NP_001262902.1	SP1-4_N	<281..>371	CDD:425404
		Atrophin-1	284..>630	CDD:460830	37/174 (21%)
		SP1-4_N	<713..741	CDD:425404	1/27 (4%)
		C2H2 Zn finger	742..764	CDD:275368	13/21 (62%)
		zf-H2C2_2	756..783	CDD:463886	18/26 (69%)
		C2H2 Zn finger	772..794	CDD:275368	15/21 (71%)
		zf-H2C2_2	786..809	CDD:463886	13/22 (59%)
		zf-C2H2	800..822	CDD:395048	16/21 (76%)
		C2H2 Zn finger	802..822	CDD:275368	15/19 (79%)