DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment KLF15 and bowl

DIOPT Version :9

Sequence 1:XP_011511045.1 Gene:KLF15 / 28999 HGNCID:14536 Length:435 Species:Homo sapiens
Sequence 2:NP_001245861.1 Gene:bowl / 33602 FlyBaseID:FBgn0004893 Length:744 Species:Drosophila melanogaster


Alignment Length:412 Identity:111/412 - (26%)
Similarity:143/412 - (34%) Gaps:138/412 - (33%)


- Green bases have known domain annotations that are detailed below.


Human    74 PDSQALCSCYGGGLGT------ESQDSILDFL-LSQATLGSG---------GGSGSSIGASSGPV 122
            |...:.....|||.|.      ...|..::.: .:.|.:|.|         ||||.|.|.|..  
  Fly     2 PTESSSSEISGGGGGAIPMLRPSRMDQFMNSMAAAAAAVGGGGLPGAADRNGGSGGSDGGSQN-- 64

Human   123 AWGPWRRAAAP--------------VKGEHFCLPEFPLGDPDDVPRPFQPTLEEIEEFLEENMEP 173
            ..|..|.::|.              :.|.|        |.|   |.|......||..|:.  :.|
  Fly    65 GNGDSRNSSASRISAYETQLAYQQHLAGLH--------GPP---PPPPPSHHREISAFVP--VLP 116

Human   174 GVKEVPEGNS------------KDL------DACSQLSAGPHKSHLHPGSSGRERCSPPPGGASA 220
            ..|..|..||            |:|      .|.:.|..||.    .||..|    .|||     
  Fly   117 TGKVRPGSNSNYEIIAMMADKRKELALREAAAAAAMLGRGPG----GPGGPG----VPPP----- 168

Human   221 GGAQGPGGGPTPDGPIPVLLQIQPVPVKQESGTGPASPGQAPENVKVAQLLVNIQGQTFALVPQV 285
            |...||.|.|.|    |.|  ..|.|....:|:.|..||.|     .|.|          ..|.:
  Fly   169 GVLYGPAGVPPP----PYL--TGPGPSPTGAGSFPFPPGAA-----AAAL----------FPPGL 212

Human   286 VPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKCTFPGCSKM 350
            .|..:..|..:.:|                .||.|..      ||       |...|.|  |::.
  Fly   213 GPGMHAGLDRRLLR----------------APGRASR------PK-------KQFICKF--CNRQ 246

Human   351 YTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHL 415
            :|||.:|..|.|.||.|:|::|..  ||..|.|.|.|..||..||..||::|..|.|.|.:|..|
  Fly   247 FTKSYNLLIHERTHTDERPYSCDI--CGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRTL 309

Human   416 SKHIKV-------HRFPRSSRS 430
            :.| |:       |:.|..|||
  Fly   310 AVH-KILHMEESPHKCPVCSRS 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KLF15XP_011511045.1 zf-C2H2 340..364 CDD:278523 9/23 (39%)
zf-C2H2_8 342..421 CDD:292531 33/78 (42%)
C2H2 Zn finger 342..364 CDD:275368 9/21 (43%)
zf-H2C2_2 356..383 CDD:290200 11/26 (42%)
C2H2 Zn finger 372..394 CDD:275368 9/21 (43%)
zf-H2C2_2 386..411 CDD:290200 11/24 (46%)
C2H2 Zn finger 402..422 CDD:275368 8/26 (31%)
bowlNP_001245861.1 COG5048 <232..372 CDD:227381 42/117 (36%)
C2H2 Zn finger 240..260 CDD:275368 9/21 (43%)
zf-H2C2_2 252..277 CDD:290200 11/26 (42%)
C2H2 Zn finger 268..288 CDD:275368 9/21 (43%)
zf-H2C2_2 280..303 CDD:290200 10/22 (45%)
C2H2 Zn finger 296..316 CDD:275368 8/20 (40%)
zf-C2H2 322..344 CDD:278523 5/9 (56%)
C2H2 Zn finger 324..344 CDD:275368 4/7 (57%)
zf-H2C2_2 336..361 CDD:290200
C2H2 Zn finger 352..372 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

Return to query results.
Submit another query.