DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment KLF15 and odd

DIOPT Version :9

Sequence 1:	XP_011511045.1	Gene:	KLF15 / 28999	HGNCID:	14536	Length:	435	Species:	Homo sapiens
Sequence 2:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	146	Identity:	49/146 - (33%)
Similarity:	65/146 - (44%)	Gaps:	37/146 - (25%)

- Green bases have known domain annotations that are detailed below.

Human   317 PGPAGL------LMGQKFPKNPAAEL-------------------IKMHKCTFPGCSKMYTKSSH 356
            |.||||      :||:.|...|..:|                   .|...|.:  |::.:|||.:
  Fly   172 PYPAGLHSLHAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQFICKY--CNRQFTKSYN 234

Human   357 LKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKV 421
            |..|.|.||.|:|::|..  ||..|.|.|.|..||..||..||::|..|.|.|.:|..|:.| ||
  Fly   235 LLIHERTHTDERPYSCDI--CGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVH-KV 296

Human   422 -------HRFPRSSRS 430
                   |:.|...||
  Fly   297 THLEEGPHKCPICQRS 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KLF15	XP_011511045.1	zf-C2H2	340..364	CDD:278523	8/23 (35%)
		zf-C2H2_8	342..421	CDD:292531	32/78 (41%)
		C2H2 Zn finger	342..364	CDD:275368	8/21 (38%)
		zf-H2C2_2	356..383	CDD:290200	11/26 (42%)
		C2H2 Zn finger	372..394	CDD:275368	9/21 (43%)
		zf-H2C2_2	386..411	CDD:290200	11/24 (46%)
		C2H2 Zn finger	402..422	CDD:275368	9/26 (35%)
odd	NP_722922.1	COG5048	<203..334	CDD:227381	39/115 (34%)
		C2H2 Zn finger	222..242	CDD:275368	8/21 (38%)
		zf-H2C2_2	234..259	CDD:290200	11/26 (42%)
		C2H2 Zn finger	250..270	CDD:275368	9/21 (43%)
		zf-H2C2_2	262..285	CDD:290200	10/22 (45%)
		C2H2 Zn finger	278..298	CDD:275368	9/20 (45%)
		zf-C2H2	304..326	CDD:278523	4/9 (44%)
		C2H2 Zn finger	306..326	CDD:275368	3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030