DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MRPL13 and mRpL13

DIOPT Version :9

Sequence 1:	NP_054797.2	Gene:	MRPL13 / 28998	HGNCID:	14278	Length:	178	Species:	Homo sapiens
Sequence 2:	NP_523598.2	Gene:	mRpL13 / 35145	FlyBaseID:	FBgn0032720	Length:	178	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	83/176 - (47%)
Similarity:	117/176 - (66%)	Gaps:	0/176 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     3 SFSRAPQQWATFARIWYLLDGKMQPPGKLAAMASIRLQGLHKPVYHALSDCGDHVVIMNTRHIAF 67
            |.::..||||||||.|::.|...|.|.:.|.:....|.||.||:||.::|||||||::|||.||.
  Fly     2 SIAKRVQQWATFARTWHIYDCTWQNPFESAKLVKTHLLGLQKPIYHPMNDCGDHVVLINTREIAL 66

Human    68 SGNKWEQKVYSSHTGYPGGFRQVTAAQLHLRDPVAIVKLAIYGMLPKNLHRRTMMERLHLFPDEY 132
            .|::|.::||..|||||||.....|.|||.:||..::|.|:|..:..||.||..|:|||||.|:.
  Fly    67 PGDEWVKRVYFHHTGYPGGASWTLAWQLHEKDPTMVMKKAVYNSMRGNLQRRHTMQRLHLFADDQ 131

Human   133 IPEDILKNLVEELPQPRKIPKRLDEYTQEEIDAFPRLWTPPEDYRL 178
            :||:||:|:..::..||.||:|||...:|.::.||.:...|:||.|
  Fly   132 VPEEILQNVTNQIRTPRSIPQRLDHIDKETLENFPNIMDYPKDYIL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MRPL13	NP_054797.2	Ribosomal_L13	16..134	CDD:395454	56/117 (48%)
mRpL13	NP_523598.2	Ribosomal_L13	16..141	CDD:278969	60/124 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147256
Domainoid	1	1.000	134	1.000	Domainoid score	I5055
eggNOG	1	0.900	-	-		E1_COG0102
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H90894
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3968
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62551
OrthoDB	1	1.010	-	-		D1119705at2759
OrthoFinder	1	1.000	-	-		FOG0003171
OrthoInspector	1	1.000	-	-		oto89744
orthoMCL	1	0.900	-	-		OOG6_101118
Panther	1	1.100	-	-	LDO	PTHR11545
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4169
SonicParanoid	1	1.000	-	-		X3602
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800