Protein Alignment HIPK2 and CG7028

DIOPT Version :9

• Sequence 1: XP_011514379.1
• Gene: HIPK2 / 28996
• HGNCID: 14402
• Length: 1377
• Species: Homo sapiens
• Sequence 2: NP_001286884.1
• Gene: CG7028 / 38032
• FlyBaseID: FBgn0027587
• Length: 912
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 150/523 - (28%)
• Similarity: 233/523 - (44%)
• Gaps: 114/523 - (21%)

Human   221 TGYGS---HSKVYSQSKNI---------PLSQPATTTVSTSLPVPNP---SLPYEQTIVFPGSTG 270
            ||..|   |:.|..:|::.         ||..|:.|     :|.|||   .:|.::.
  Fly   463 TGQESPAPHNSVSYESRSTSQGSSQRERPLRTPSPT-----MPCPNPLISEIPKDRE-------- 514

Human   271 HIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQK-CGLKRKSEEIEN------TSSVQIIEE 328
                ...:|||                        || |..|.|..|.:.      .|:..:..:
  Fly   515 ----DMDNSTS------------------------QKTCSAKEKRNEWDMFADQDVDSNFDVSRK 551

Human   329 HPP--MIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQ 391
            ..|  ::||.......|..        ::..::||.|::...|||   .|.|.|..:.|:|.|..
  Fly   552 ISPNTIVQNKHQHENPALT--------DNWDDAEGYYRVRIGEVL---DNRYLVNGYTGQGVFSN 605

Human   392 VVKCWKRGTNEI-----VAIKILKNHPSYARQGQIEVSILARLSTESADD-YNFVRAYECFQHKN 450
            ||    ||.::.     |||||::|:....:.|..|:.||.:|:....:| ::.:|.|..|.||.
  Fly   606 VV----RGRDQARGQANVAIKIIRNNEIMHKTGLRELEILKKLNDADPEDRFHCLRLYRHFFHKQ 666

Human   451 HTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDP 514
            |.|:|||.|..||.:.||: .|...|.:|.:|...||:..||..||..|::|||:||:||::
  Fly   667 HLCMVFEPLAMNLREVLKKYGKNVGLHIKAVRSYTQQLFLALKLLKKTGILHADIKPDNILV--- 728

Human   515 SRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPL 579
            :.....:|:.||||||.:|....:.||.||:||:||||||:|:...||.||.||.|.||:.|..|
  Fly   729 NENNLILKLCDFGSASAISDNEITPYLVSRFYRSPEIILGIPYDYGIDTWSAGCTIYELYTGKIL 793

Human   580 YPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEA 644
            :.|.|....:::....:|.....::..|....:.|::..:..|          ||.:   |..|.
  Fly   794 FSGKSNNQMLKFFMDVKGKIPNRIIRKGQFREQHFDQSCNFLY----------HEID---KLTER 845

Human   645 RKYIFNCLDDMAQV----NMTTDLEGSDMLVEKADRR--EFIDLLKKMLTIDADKRITPIETLNH 703
            .|.:.     |..|    ::..:|.....|.:...|:  :..|||:.|..:|..|||:..:.|.|
  Fly   846 EKIVV-----MPVVKPSRSLQQELIADQNLPDDQHRKVTQLKDLLENMFALDPAKRISLNQALVH 905

Human   704 PFV 706
            ||:
  Fly   906 PFI 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPK2	XP_011514379.1	STKc_HIPK2	362..716	CDD:271129	119/358 (33%)
		S_TKc	378..706	CDD:214567	113/340 (33%)
CG7028	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	113/341 (33%)
		S_TKc	599..908	CDD:214567	111/333 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810