Protein Alignment BZW2 and kra

DIOPT Version :10

• Sequence 1: NP_054757.1
• Gene: BZW2 / 28969
• HGNCID: 18808
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_524238.1
• Gene: kra / 40680
• FlyBaseID: FBgn0250753
• Length: 422
• Species: Drosophila melanogaster
• Alignment Length: 416
• Identity: 209/416 - (50%)
• Similarity: 305/416 - (73%)
• Gaps: 1/416 - (0%)

Human     3 KHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADT 67
            |.::|||:|||.|||||||:||::||.|||.::.||.:...|||.::|:|||.|::||||||.:.
  Fly     4 KTERPVLSGQRIKTRKRDEREKYDPTGFRDAVIAGLEKTEGDLEQISKYLDSAGNKLDYRRYGEV 68

Human    68 LFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDE 132
            |||||:||.:|.|||:...||:|.: |::|:|.|.|..|::||:.|||.|||||||||||.||:|
  Fly    69 LFDILIAGGLLVPGGSISQDGEKPR-TSYCIFDAPESMESMRNHEQVFVKLIRRYKYLEKMFEEE 132

Human   133 MKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAE 197
            |.|:|||:|.|:.:|:.|||.::.:.|.||::|..:|..|..:.|:|:|||..|.::||:.:..|
  Fly   133 MGKVLLFVKGFTPSERIKLARMTALWLVNGSVPPNVLLVLNNEHLIKDGIALEFLLELFQTFKQE 197

Human   198 KDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKEL 262
            |....:..:|:|..|:.:|::.||.|:::.::|.:.|.|..|.|:....:.|.|...::|||:.|
  Fly   198 KGIAYLIQALKKGGLESKLMDFFPPNKRTEEYFKQVFLDKELNEIVKLHKAQASQEAKRELQQAL 262

Human   263 QERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAP 327
            .:.::.|.|..|:...:|:..:|.::|:..:|.::|:.||:..|||||||||.:||::|||.|.|
  Fly   263 IDDINDEKPYNEITSDIKDFSQRTNIPDHEIIVIIWSTIMSLGEWNKKEELVTDQAVRHLKNYCP 327

Human   328 LLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKS 392
            ||..|:|..:|||.|:.||||:||:|::||||||||::||||.:|||||.||:||||.|..|||.
  Fly   328 LLQAFASTDRSELALILKVQEFCYENMNFMKAFQKIILLFYKTEVLSEEIILRWYKEGHSNKGKM 392

Human   393 VFLDQMKKFVEWLQNAEEESESEGEE 418
            .||:||:|||||||:||||||||.|:
  Fly   393 HFLEQMRKFVEWLQSAEEESESEDEQ 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BZW2	NP_054757.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		13/18 (72%)
		W2_eIF5C_like	218..408	CDD:211398	93/189 (49%)
kra	NP_524238.1	W2_eIF5C_like	218..406	CDD:211398	91/187 (49%)