Protein Alignment TRIB2 and PRR1

DIOPT Version :10

• Sequence 1: NP_067675.1
• Gene: TRIB2 / 28951
• HGNCID: 30809
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_012806.1
• Gene: PRR1 / 853744
• SGDID: S000001599
• Length: 518
• Species: Saccharomyces cerevisiae
• Alignment Length: 327
• Identity: 69/327 - (21%)
• Similarity: 127/327 - (38%)
• Gaps: 88/327 - (26%)

Human    25 EELSSIRSAEPSQSFSPNLGSPSPPET------PNLSHCVSCIGKYL-LLEPLEGDHVFRAVHLH 82
            ||||::.....|..:...|.......|      .:|:|  .||.|.| :..|:          ..
Yeast   231 EELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNH--PCIVKLLGINNPI----------FV 283

Human    83 SGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEIIL---GETKAYVFFERSYGDMHSFVRTC 144
            :.::.:|.:  |.....:|.||..:.::.....:...::   |..:|::.
Yeast   284 TSKKPLCDL--IIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLI--------------- 331

Human   145 KKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLR----KFIFKDEERTRVKLESLEDA------ 199
                    .|:|.::..||.:.|:..::.|||||.    |:.|.|       :.|..|:
Yeast   332 --------QRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDD-------INSFRDSPIYCKQ 381

Human   200 -YILRGD---------DDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPF 254
             :|...|         ::..:.:.|...||||||| ....|.|..:|.|:|||:||::...|.||
Yeast   382 NFIELADFGLCKKIENNEMCTARCGSEDYVSPEIL-MGVPYDGHLSDTWALGVILYSLFEDRLPF 445

Human   255 HDIEPSSLFSKIRRGQ-----------FNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWF 308
             |..|::...:..|..           :.:.:..:...|.::.:.|.|: ::|.:..||.:.|:.
Yeast   446 -DPPPNASARQRSRATSHRIARFDWRWYRLSDYKTNVGKQIVENTLTRK-NQRWSINEIYESPFV 508

Human   309 ST 310
            .|
Yeast   509 KT 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB2	NP_067675.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..50		6/24 (25%)
		PK_TRB2	67..308	CDD:270924	55/274 (20%)
PRR1	NP_012806.1	S_TKc	192..508	CDD:214567	68/323 (21%)