Protein Alignment TRIB2 and SNF1

DIOPT Version :10

• Sequence 1: NP_067675.1
• Gene: TRIB2 / 28951
• HGNCID: 30809
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_010765.3
• Gene: SNF1 / 852088
• SGDID: S000002885
• Length: 633
• Species: Saccharomyces cerevisiae
• Alignment Length: 285
• Identity: 90/285 - (31%)
• Similarity: 135/285 - (47%)
• Gaps: 26/285 - (9%)

Human    44 GSPSPPETPNLS-----HCVSCIGKYLLLEPL-EGD--HVFRAVHLHSGEELVCKVF-------- 92
            ||.|....|..|     |    ||.|.:::.| ||.  .|..|.|..:|:::..|:.
Yeast    34 GSNSTLNNPKSSLADGAH----IGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKS 94

Human    93 DISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFY 157
            |:....|.......|..|.:|.::.::|..:.:..:..|.:..::..::....|:.|:||.|.|.
Yeast    95 DMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQ 159

Human   158 QIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPE 222
            ||.|||.:||...:|.||||....:.  :|...||:.....:.|:. |.:.|....|.|.|.:||
Yeast   160 QIISAVEYCHRHKIVHRDLKPENLLL--DEHLNVKIADFGLSNIMT-DGNFLKTSCGSPNYAAPE 221

Human   223 ILNTSGS-YSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIR 286
            ::  ||. |:|...||||.||:||.||..|.||.|.....||..|..|.:.:|:.|||.|..||:
Yeast   222 VI--SGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIK 284

Human   287 SILRREPSERLTSQEILDHPWFSTD 311
            .:|...|..|::..||:...||..|
Yeast   285 RMLIVNPLNRISIHEIMQDDWFKVD 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB2	NP_067675.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..50		3/5 (60%)
		PK_TRB2	67..308	CDD:270924	78/252 (31%)
SNF1	NP_010765.3	STKc_AMPK_alpha	52..306	CDD:270981	81/258 (31%)
		UBA_2	344..389	CDD:430091
		AdenylateSensor	504..626	CDD:406881