Protein Alignment TRIB2 and trbl

DIOPT Version :9

• Sequence 1: NP_067675.1
• Gene: TRIB2 / 28951
• HGNCID: 30809
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_524672.1
• Gene: trbl / 43999
• FlyBaseID: FBgn0028978
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 121/350 - (34%)
• Similarity: 181/350 - (51%)
• Gaps: 61/350 - (17%)

Human    32 SAEPSQSFSPNLGSPSPPETP-NLSHCVSCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKV---- 91
            ||:||     ::.:....:|| :..|.|......|           |.|.:.:||:.:|::
  Fly   111 SAQPS-----HISAAVAAKTPASYRHLVDLTASNL-----------RCVDIFTGEQFLCRIVNEP 159

Human    92 --------FDISCYQESLAPCFCLSAHSNINQITEII-LGETKAYVFF-----ERS--------Y 134
                    |.:..:.|.|... .:..|..|..:.:|| |.:.:.|:..     ||.        |
  Fly   160 LHKVQRAYFQLQQHDEELRRS-TIYGHPLIRPVHDIIPLTKDRTYILIAPVPQERDSTGGVTGVY 223

Human   135 GDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDA 199
            .::|:::|..|:|.|.||..:|:||...|..||..|::||||||::|.|.||.||:::.||||.:
  Fly   224 ENLHTYIRHAKRLCETEARAIFHQICQTVQVCHRNGIILRDLKLKRFYFIDEARTKLQYESLEGS 288

Human   200 YILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFS 264
            .||.|:||:||||.|||.|.:||:|....:|.||.||:|||||:|||||||:|||::....:|.:
  Fly   289 MILDGEDDTLSDKIGCPLYTAPELLCPQQTYKGKPADMWSLGVILYTMLVGQYPFYEKANCNLIT 353

Human   265 KIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPW----------FSTDFSVSNSAY 319
            .||.|...||.|||...:.|:.|:||::.:||:|:..|...||          ...|..|:....
  Fly   354 VIRHGNVQIPLTLSKSVRWLLLSLLRKDYTERMTASHIFLTPWLREQRPFHMYLPVDVEVAEDWS 418

Human   320 GAKE----VSDQLVPDVNMEENLDP 340
            .|:|    .:|.:..|   ||.|.|
  Fly   419 DAEEDEGTAADAMDDD---EEGLCP 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB2	NP_067675.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..50		4/17 (24%)
		PK_TRB2	67..308	CDD:270924	102/276 (37%)
trbl	NP_524672.1	PKc_like	131..397	CDD:328722	104/277 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159492
Domainoid	1	1.000	181	1.000	Domainoid score	I3485
eggNOG	1	0.900	-	-		E33208_3BAWK
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41445
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3953
Isobase	1	0.950	-	0	Normalized mean entropy	S3244
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1362510at2759
OrthoFinder	1	1.000	-	-		FOG0001790
OrthoInspector	1	1.000	-	-		otm40776
orthoMCL	1	0.900	-	-		OOG6_108152
Panther	1	1.100	-	-	LDO	PTHR22961
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5302
SonicParanoid	1	1.000	-	-		X1487
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.740