Protein Alignment TRIB2 and ppk27

DIOPT Version :10

• Sequence 1: NP_067675.1
• Gene: TRIB2 / 28951
• HGNCID: 30809
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_595405.1
• Gene: ppk27 / 2540313
• PomBaseID: SPBC337.04
• Length: 413
• Species: Schizosaccharomyces pombe
• Alignment Length: 281
• Identity: 61/281 - (21%)
• Similarity: 111/281 - (39%)
• Gaps: 69/281 - (24%)

Human    75 VFRAVHLHS----GEELVCKVF--DISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERS 133
            |.:..||.|    .::...|||  :|...:....||.....:..::. .|:||.|         :
pombe   131 VLKHTHLSSKSQNEKKARVKVFRQEIWALKTLSHPCVVQLLNYYVSS-AELILVE---------N 185

Human   134 Y---GDMHSFVRTCKKLRE----EEAARLFYQIASAVAHCHDGGLVLRDLKLRKFI--------- 182
            |   ||::.:.   ||...    |...|:|.::...||:.|...|:.|||||...:
pombe   186 YCMGGDLYHYT---KKHHSDFSLEFVGRIFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIK 247

Human   183 ----FKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVM 243
                :|:.....:::...|.:..:...:..:....|...|..||:. ...::.|..||.||||::
pombe   248 TIDNWKNYPNALIQISDFELSIFVDSKNHLVQSSCGSQEYAPPEVY-MGIAHDGFRADAWSLGIV 311

Human   244 LYTMLVGRYPFHD---IEPSSLFSKIRR-----------------------GQFNIPETLSPKAK 282
            |:.:|.||.||..   ::|.::  :|:|                       |..|..:..|.:.:
pombe   312 LFALLEGRLPFDSYPTLDPENV--RIKRYVQRLVRCDYTWHLCKSPFKRSTGNTNDNDDPSWRFR 374

Human   283 CLIRSILRREPSERLTSQEIL 303
            ..::.:|:.. .:|.|..|:|
pombe   375 LFVKKLLKNR-DQRSTPTELL 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB2	NP_067675.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..50
		PK_TRB2	67..308	CDD:270924	61/281 (22%)
ppk27	NP_595405.1	Protein Kinases, catalytic domain	144..396	CDD:473864	57/268 (21%)